{"id":"W4376112385","doi":"10.1016/s1465-3249(23)00242-6","title":"Mesenchymal Stem/Stromal Cells: ON DEMAND MANUFACTURING STRATEGY TO DELIVER MULTIPLE DOSES OF FRESHLY CULTURED UMBILICAL CORD DERIVED MSCS IN THE CELLULAR IMMUNO-THERAPY FOR COVID-19 RELATED ARDS CLINICAL TRIAL","year":2023,"lang":"en","type":"article","venue":"Cytotherapy","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; Children's Hospital of Eastern Ontario; Ottawa Hospital","funders":"","keywords":"Mesenchymal stem cell; Umbilical cord; Medicine; Cell therapy; ARDS; Clinical trial; Stromal cell; Immunology; Stem cell; Pathology; Biology; Cell biology; Internal medicine; Lung","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003731368,0.0004307387,0.00105048,0.0003623008,0.000207612,0.00007212459,0.0006068979,0.000504096,0.0003528218],"category_scores_gemma":[0.0006176045,0.0002918732,0.0005542914,0.0006567214,0.0002799973,0.0000731244,0.00006579945,0.0007559225,0.00009677455],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001985429,"about_ca_system_score_gemma":0.0003927889,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002273077,"about_ca_topic_score_gemma":0.00009780453,"domain_scores_codex":[0.994713,0.001049686,0.001438109,0.0008732802,0.001070061,0.0008558314],"domain_scores_gemma":[0.9949402,0.003250462,0.0002670426,0.0009054532,0.000148708,0.0004881407],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.3066461,0.002115374,0.004843983,0.0003155923,0.0006135066,0.0004748033,0.00419739,0.001466475,0.6462376,0.0001176976,0.007523949,0.02544756],"study_design_scores_gemma":[0.2506366,0.04476062,0.03042953,0.0003306342,0.0001111319,0.00003717842,0.004504784,0.003771886,0.6308259,0.0004120171,0.03318585,0.000993939],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908714,0.0004786973,0.0003635035,0.001056789,0.0003757809,0.006466047,0.00007542819,0.0001200221,0.0001923345],"genre_scores_gemma":[0.9957554,0.0009613112,0.0004103156,0.0009193412,0.0003509037,0.0004618434,0.00009265038,0.00008819607,0.0009600525],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05600949,"threshold_uncertainty_score":0.9999533,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1980565869126888,"score_gpt":0.4371970460036622,"score_spread":0.2391404590909735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}