{"id":"W4376112385","doi":"10.1016/s1465-3249(23)00242-6","title":"Mesenchymal Stem/Stromal Cells: ON DEMAND MANUFACTURING STRATEGY TO DELIVER MULTIPLE DOSES OF FRESHLY CULTURED UMBILICAL CORD DERIVED MSCS IN THE CELLULAR IMMUNO-THERAPY FOR COVID-19 RELATED ARDS CLINICAL TRIAL","year":2023,"lang":"en","type":"article","venue":"Cytotherapy","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; Children's Hospital of Eastern Ontario; Ottawa Hospital","funders":"","keywords":"Mesenchymal stem cell; Umbilical cord; Medicine; Cell therapy; ARDS; Clinical trial; Stromal cell; Immunology; Stem cell; Pathology; Biology; Cell biology; Internal medicine; Lung","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004080571,0.000332466,0.0002794943,0.0004081639,0.0001845219,0.0004999685,0.0002213606,0.0003832837,0.002806636],"category_scores_gemma":[0.0002217813,0.0001684409,0.0003685253,0.0002831336,0.0001356095,0.0001509417,0.0002196338,0.0006607972,0.001026881],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001843045,"about_ca_system_score_gemma":0.0003599126,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004111451,"about_ca_topic_score_gemma":0.001140511,"domain_scores_codex":[0.999769,0.00003815044,0.00002607849,0.00004230455,0.0001000177,0.00002447283],"domain_scores_gemma":[0.9998987,0.00002130523,0.00002235364,0.00001448613,0.00002074516,0.00002235889],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003462028,0.0002103562,0.0003046991,0.00009876786,0.00001400035,0.0000835493,0.00003175798,0.0004787594,0.9834756,0.0002895346,0.0003657595,0.01430103],"study_design_scores_gemma":[0.0001034176,0.001305075,0.001590657,0.00001123716,0.00007674693,0.0001881939,0.00003584734,0.003054474,0.9845484,0.0001095488,0.008963397,0.00001285738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8911468,0.004351862,0.08860194,0.0005797922,0.0006339245,0.001853293,0.00171505,0.0004676344,0.0106496],"genre_scores_gemma":[0.9373301,0.001972427,0.05377684,0.00036256,0.0001161954,0.0009998443,0.0008730125,0.00009418478,0.004474863],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002806636,"threshold_uncertainty_score":0.009389102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1980565869126888,"score_gpt":0.4371970460036622,"score_spread":0.2391404590909735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}