{"id":"W4376115779","doi":"10.3390/cancers15102683","title":"The Epigenetic Reader Methyl-CpG-Binding Protein 2 (MeCP2) Is an Emerging Oncogene in Cancer Biology","year":2023,"lang":"en","type":"review","venue":"Cancers","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"MECP2; Epigenetics; Oncogene; Biology; CpG site; DNA methylation; Computational biology; Genetics; Cancer; Cancer research; Phenotype; Gene; Gene expression; Cell cycle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003272631,0.000691527,0.00072299,0.001635544,0.0002492282,0.0007128178,0.0006202497,0.0008833248,0.002845228],"category_scores_gemma":[0.0004214596,0.0001498553,0.0002778256,0.001868944,0.0004258432,0.001078435,0.0006095646,0.001415594,0.001879461],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006674023,"about_ca_system_score_gemma":0.001017453,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00122242,"about_ca_topic_score_gemma":0.001656934,"domain_scores_codex":[0.9998938,0.00001484809,0.00001130551,0.00002262001,0.00004303106,0.00001436902],"domain_scores_gemma":[0.9998276,0.00006777446,0.00002107927,0.00000506762,0.00005447675,0.00002389032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004836448,0.00003966958,0.0002290171,0.006681807,0.00003709457,0.000233443,0.0000454712,0.0002727874,0.002523652,0.005071552,0.03944188,0.9453752],"study_design_scores_gemma":[0.000005161443,0.00003556848,0.0004459421,0.0009471097,0.00003722471,0.001000099,0.00002644818,0.00004548566,0.0004835922,0.0012811,0.9956827,0.000009529702],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001215154,0.9976442,0.000185315,0.0003529539,0.000228607,0.000003194526,0.00002145876,0.00001208332,0.001430619],"genre_scores_gemma":[0.0008334896,0.9975789,0.0002123916,0.0001964384,0.0001719986,0.000004672711,0.00004298728,0.000001956264,0.0009572902],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002845228,"threshold_uncertainty_score":0.009518206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08975279017306761,"score_gpt":0.3842367317768192,"score_spread":0.2944839416037516,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}