{"id":"W4376121502","doi":"10.1002/bit.28420","title":"Fouling of virus filtration membranes by monoclonal antibody feeds with low aggregate content","year":2023,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Membrane Separation Technologies","field":"Environmental Science","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Membrane; Fouling; Membrane fouling; Chemistry; Ultrafiltration (renal); Filtration (mathematics); Monoclonal antibody; Chromatography; Adsorption; Permeability (electromagnetism); Chemical engineering; Antibody; Biochemistry; Organic chemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001033971,0.0001284881,0.0001523697,0.0001282724,0.00006476683,0.00001017914,0.0001464336,0.000226671,0.00003680462],"category_scores_gemma":[0.00002554078,0.0001054571,0.00001873164,0.0004846088,0.0003003607,0.0001119024,0.00009815119,0.000131236,0.00002883164],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001700216,"about_ca_system_score_gemma":0.000003313003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005811144,"about_ca_topic_score_gemma":0.00001957595,"domain_scores_codex":[0.9992846,0.000006418022,0.0001662902,0.0002272378,0.0001124942,0.0002030015],"domain_scores_gemma":[0.9997092,0.00002527105,0.00006824823,0.0001668602,0.000005399345,0.00002501822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001192442,0.00001141338,0.001776851,0.0000336804,0.00001783758,0.000005402071,0.00002596852,0.001751935,0.9930304,0.0002236441,0.00005555772,0.003055339],"study_design_scores_gemma":[0.000208221,0.0001189168,0.002666046,0.00003067434,0.000008699077,0.00001662564,0.0001045411,0.01108496,0.9848939,0.00003582497,0.0006970345,0.0001345864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939243,0.0002508386,0.00410897,0.0008793039,0.00004487163,0.0001357472,0.00001231618,0.0005972617,0.00004639592],"genre_scores_gemma":[0.9976917,0.0007906262,0.001355058,0.00001467593,0.000005605896,0.00001146754,0.00002270912,0.00001050184,0.00009765183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009333021,"threshold_uncertainty_score":0.4300417,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0131278003363823,"score_gpt":0.2211270193123636,"score_spread":0.2079992189759813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}