{"id":"W4376121502","doi":"10.1002/bit.28420","title":"Fouling of virus filtration membranes by monoclonal antibody feeds with low aggregate content","year":2023,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Membrane Separation Technologies","field":"Environmental Science","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Membrane; Fouling; Membrane fouling; Chemistry; Ultrafiltration (renal); Filtration (mathematics); Monoclonal antibody; Chromatography; Adsorption; Permeability (electromagnetism); Chemical engineering; Antibody; Biochemistry; Organic chemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003435719,0.0002709058,0.0002313266,0.0001778548,0.0002367226,0.0003167345,0.0002206226,0.0004535909,0.0003793406],"category_scores_gemma":[0.0005846546,0.00009782859,0.0002728706,0.0002058419,0.0001419251,0.0002855882,0.0002124095,0.0004818639,0.0001347186],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003407545,"about_ca_system_score_gemma":0.0001702853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001861511,"about_ca_topic_score_gemma":0.001595083,"domain_scores_codex":[0.9996963,0.00004882935,0.00002352357,0.00004817696,0.000106788,0.00007646274],"domain_scores_gemma":[0.9997873,0.00006761802,0.00005472658,0.00001605661,0.00005717427,0.00001710141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001573966,0.000005826996,0.0001881217,0.00001638369,0.000003752323,0.00001275803,0.00002232885,0.00004459036,0.9991804,0.00002069067,0.000009883416,0.0004794718],"study_design_scores_gemma":[6.882385e-7,0.00005264658,0.001000135,0.000002189087,0.000003976218,0.00002049814,0.00001431033,0.0002866408,0.9984109,0.000007711777,0.0001986012,0.000001712915],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975677,0.0004233694,0.001620478,0.00002593396,0.00001016508,0.000005312979,0.00004377343,0.00001621275,0.000287182],"genre_scores_gemma":[0.9958963,0.0005114232,0.002595017,0.00003702174,0.00000590155,0.00001178701,0.0001228443,0.00001384522,0.0008057287],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001861511,"threshold_uncertainty_score":0.003701329,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0131278003363823,"score_gpt":0.2211270193123636,"score_spread":0.2079992189759813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}