{"id":"W4376121868","doi":"10.1007/s40266-023-01032-6","title":"Impact of a Comprehensive Intervention Bundle Including the Drug Burden Index on Deprescribing Anticholinergic and Sedative Drugs in Older Acute Inpatients: A Non-randomised Controlled Before-and-After Pilot Study","year":2023,"lang":"en","type":"article","venue":"Drugs & Aging","topic":"Pharmaceutical Practices and Patient Outcomes","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nova Scotia Health Authority; Dalhousie University","funders":"National Health and Medical Research Council; Medical Research Council; NSW Ministry of Health; Dementia Australia; University of Sydney; Central Coast Local Health District; Royal North Shore Hospital","keywords":"Medicine; Anticholinergic; Deprescribing; Drug; Sedative; Pharmacotherapy; Intervention (counseling); Polypharmacy; Intensive care medicine; Anesthesia; Emergency medicine; Pharmacology; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005216504,0.001753042,0.002855843,0.000951221,0.00105094,0.001224525,0.001338004,0.002256883,0.005493665],"category_scores_gemma":[0.006895441,0.0009307758,0.002668637,0.000900251,0.001591308,0.001434108,0.001846913,0.002571607,0.0005773429],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002814506,"about_ca_system_score_gemma":0.004181694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006710191,"about_ca_topic_score_gemma":0.009416019,"domain_scores_codex":[0.9943377,0.002852862,0.0006851546,0.0006746342,0.0005637304,0.0008858555],"domain_scores_gemma":[0.9937453,0.001642105,0.001623585,0.0005072333,0.0005398288,0.001941932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7222038,0.2379529,0.004802582,0.001162287,0.00105257,0.0000755541,0.0003699282,0.0005635357,0.001295481,0.00007337076,0.0004899615,0.02995804],"study_design_scores_gemma":[0.3783783,0.5999746,0.01951107,0.00009164368,0.0004804804,0.00001600548,0.0001242775,0.0004779591,0.00048463,0.00006903241,0.0003610044,0.00003099487],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838079,0.0003217961,0.000360375,0.0001778014,0.0002293207,0.0141359,0.000339692,0.00006257303,0.0005646869],"genre_scores_gemma":[0.9718344,0.0004828293,0.003271326,0.0003629994,0.0004983325,0.02201151,0.0004367,0.00001243461,0.001089492],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006710191,"threshold_uncertainty_score":0.02758789,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05248098706810838,"score_gpt":0.395154338715658,"score_spread":0.3426733516475496,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}