{"id":"W4376133598","doi":"10.1126/sciadv.ade4443","title":"Functional neuronal circuits promote disease progression in cancer","year":2023,"lang":"en","type":"article","venue":"Science Advances","topic":"Cancer, Stress, Anesthesia, and Immune Response","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Institute of Dental and Craniofacial Research; National Institute of General Medical Sciences","keywords":"Neuroscience; Immunohistochemistry; Biology; Neuropeptide; Gene silencing; Cancer; Receptor; Pathology; Cancer research; Tumor progression; Disease; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009141237,0.0001109515,0.000103224,0.0001859355,0.0001222146,0.0002466791,0.00005971098,0.0001647778,0.0009423138],"category_scores_gemma":[0.0001313637,0.0000439444,0.00008020892,0.0001111415,0.0001424093,0.0001543612,0.0001568191,0.0002821763,0.0001177399],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002413345,"about_ca_system_score_gemma":0.0001386405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002623709,"about_ca_topic_score_gemma":0.0004954335,"domain_scores_codex":[0.999954,0.000008657275,0.000002914412,0.000008574484,0.00001186752,0.00001401605],"domain_scores_gemma":[0.9999371,0.000008726824,0.00002436227,0.000003832693,0.000009689728,0.00001636052],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004397932,0.0002074767,0.02150669,0.0002485419,0.00004195329,0.00062544,0.0001683277,0.0005311094,0.9184984,0.001961991,0.0005553283,0.05521493],"study_design_scores_gemma":[0.00007406079,0.003856896,0.5682302,0.0001035242,0.0001637793,0.00586247,0.0007873862,0.004474686,0.3828064,0.003425273,0.03019112,0.00002420197],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860166,0.008356737,0.001145359,0.0002362697,0.00001916269,0.00002296122,0.00008328849,0.00004681534,0.004072851],"genre_scores_gemma":[0.9971602,0.001707667,0.0002690073,0.00004060482,0.000007302168,0.00001157365,0.00005233783,0.000002175222,0.0007491917],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009423138,"threshold_uncertainty_score":0.00315237,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02823257820988135,"score_gpt":0.34325893892987,"score_spread":0.3150263607199887,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}