{"id":"W4376134070","doi":"10.1186/s13578-023-01024-4","title":"ISG15 suppresses ovulation and female fertility by ISGylating ADAMTS1","year":2023,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Agriculture","funders":"Science and Technology Service Network Plan; Jiangsu Provincial Key Research and Development Program; Key Technologies Research and Development Program of Anhui Province","keywords":"Fertility; Ovulation; ISG15; Gynecology; Biology; Andrology; Demography; Medicine; Pregnancy; Population; Sociology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002903352,0.0001047587,0.0001188076,0.00007573797,0.0003103594,0.00003917421,0.0001717006,0.0000986572,0.0002742409],"category_scores_gemma":[0.000150881,0.00009001064,0.00002871444,0.0002679348,0.0003435689,0.0001626923,0.0001369487,0.0001155585,0.0004911051],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001394779,"about_ca_system_score_gemma":0.0000302578,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006685803,"about_ca_topic_score_gemma":0.000004541001,"domain_scores_codex":[0.9990889,0.0001068854,0.0001622788,0.0002990481,0.00003558294,0.0003072923],"domain_scores_gemma":[0.9995552,0.000154825,0.00005323358,0.0001847952,0.00003223033,0.00001977222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000464937,0.00002289675,0.003771961,0.0000130736,0.000002572961,7.895007e-7,0.0003988282,0.000001172147,0.9894016,0.00002209529,0.004573547,0.001744983],"study_design_scores_gemma":[0.0002510875,0.0001051426,0.07500689,0.0000148832,0.000004783029,0.000005195493,0.0004753305,0.0001235741,0.9016376,0.00002720907,0.02222648,0.0001218711],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956129,0.001644126,0.00009741735,0.0001808829,0.0004200962,0.00009972695,0.00002155417,0.0001092999,0.001813998],"genre_scores_gemma":[0.9867876,0.00008054701,0.00003022715,0.0001022842,0.000004936828,0.000005582749,0.00003225622,0.000005996219,0.01295054],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08776403,"threshold_uncertainty_score":0.6312326,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01507874257407486,"score_gpt":0.2509775374343349,"score_spread":0.2358987948602601,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}