{"id":"W4376134197","doi":"10.1515/psr-2022-0288","title":"Dipeptidyl peptidase IV: a multifunctional enzyme with implications in several pathologies including cancer","year":2023,"lang":"en","type":"article","venue":"Physical Sciences Reviews","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Ministerio de Ciencia, Tecnología y Medio Ambiente","keywords":"Cancer; Dipeptidyl peptidase-4; Immune system; Dipeptidyl peptidase; Cancer cell; Tumor microenvironment; Biology; Cell signaling; Cancer research; Enzyme; Computational biology; Chemistry; Signal transduction; Diabetes mellitus; Medicine; Cell biology; Immunology; Biochemistry; Type 2 diabetes; Endocrinology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000175658,0.0003650817,0.0002553307,0.0006439028,0.0001267396,0.0004941358,0.0001721037,0.0003833576,0.0008468009],"category_scores_gemma":[0.00008002091,0.00007433721,0.0001321832,0.0003708298,0.0003156905,0.0003486787,0.0002609757,0.0005007376,0.0004905384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002746151,"about_ca_system_score_gemma":0.0002961219,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002222843,"about_ca_topic_score_gemma":0.0002685561,"domain_scores_codex":[0.99994,0.0000110615,0.000007218528,0.00001188758,0.00001913903,0.00001051492],"domain_scores_gemma":[0.9999577,0.000008546668,0.00001267081,0.00000163434,0.000008651563,0.00001080534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0004681758,0.00013713,0.001380427,0.00489856,0.00007969017,0.001169282,0.0001374421,0.0008314339,0.2282889,0.01635378,0.01590113,0.7303541],"study_design_scores_gemma":[0.00003355001,0.001008142,0.007024448,0.0007685458,0.0001227919,0.006692731,0.0001691409,0.000590161,0.06749298,0.007326812,0.9087422,0.00002853401],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01009364,0.9808003,0.002416639,0.001402716,0.0005743564,0.000009948597,0.00005920356,0.00002943138,0.004613873],"genre_scores_gemma":[0.07945012,0.9062619,0.003158475,0.0007470701,0.001058151,0.00001739576,0.0001254654,0.000009835449,0.009171669],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0008468009,"threshold_uncertainty_score":0.00283283,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1484101106785772,"score_gpt":0.4147360951065573,"score_spread":0.2663259844279801,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}