{"id":"W4376139859","doi":"10.1007/s11051-023-05758-7","title":"Phytoglycogen-dsRNA nanoparticles demonstrate differential cytotoxicity and immunostimulatory potential in two ovarian cancer cell lines","year":2023,"lang":"en","type":"article","venue":"Journal of Nanoparticle Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mirexus (Canada); Wilfrid Laurier University","funders":"","keywords":"Cancer cell; Immune system; Cytotoxicity; Biology; Cell biology; Cancer; Medicine; Biochemistry; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001659278,0.0002363514,0.0002149472,0.0002067855,0.0001506628,0.0002424789,0.0001422376,0.0003651283,0.0008015228],"category_scores_gemma":[0.000112723,0.0001210238,0.0002062344,0.0001586642,0.0001884563,0.0001878345,0.0001336312,0.0004628594,0.0002222315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001884683,"about_ca_system_score_gemma":0.0001477897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006829125,"about_ca_topic_score_gemma":0.001112093,"domain_scores_codex":[0.9998393,0.0000242593,0.00002073204,0.00003185982,0.00005283253,0.00003101729],"domain_scores_gemma":[0.9998727,0.00005368673,0.00001740772,0.0000206982,0.00002248948,0.00001297737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004987929,0.00001348931,0.00007657174,0.00001518095,0.000001966022,0.00002037819,0.00001757974,0.00002530755,0.9993243,0.00004785449,0.00001576932,0.0003916495],"study_design_scores_gemma":[0.000005222045,0.00008095081,0.0006591282,7.562302e-7,0.000005799725,0.00005275407,0.00001209756,0.0001909829,0.998625,0.000008279833,0.0003578171,0.000001124029],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922465,0.0005186153,0.004567662,0.0000897039,0.00002703307,0.00003647434,0.0003101469,0.00007727917,0.002126401],"genre_scores_gemma":[0.9922152,0.0003552645,0.003013131,0.00005874566,0.000005397973,0.00006220289,0.0005016662,0.00001912164,0.003769113],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008015228,"threshold_uncertainty_score":0.002681375,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03993495321257827,"score_gpt":0.3667227708940246,"score_spread":0.3267878176814463,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}