{"id":"W4376225657","doi":"10.1016/j.jcrc.2023.154318","title":"Major adverse cardiovascular events (MACE) in patients with severe COVID-19 registered in the ISARIC WHO clinical characterization protocol: A prospective, multinational, observational study","year":2023,"lang":"en","type":"article","venue":"Journal of Critical Care","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Instituto de Salud Carlos III; Canadian Institutes of Health Research; Michigan Institute for Clinical and Health Research; Prince Charles Hospital Foundation; National Institutes of Health; Kementerian Kesihatan Malaysia; All-India Institute of Medical Sciences; University of Cape Town; Public Health England; Wellcome Trust; Cancer Research UK; University College Dublin; European Commission; Foreign, Commonwealth and Development Office; National Institute for Health Research Health Protection Research Unit; University of Oxford; Norges Forskningsråd; University of Queensland; Ministère des Affaires Sociales et de la Santé; European Federation of Pharmaceutical Industries and Associations; National Institute for Health and Care Research; Ministero della Salute; Institut National de la Santé et de la Recherche Médicale; Sunnybrook Research Institute; Innovative Medicines Initiative; Imperial College London; Australian Research Council; Firland Foundation; Bill and Melinda Gates Foundation; Manchester Biomedical Research Centre; Liverpool Experimental Cancer Medicine Centre","keywords":"Mace; Medicine; Prospective cohort study; Internal medicine; Incidence (geometry); Odds ratio; Cohort study; Confounding; Percutaneous coronary intervention; Myocardial infarction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00307045,0.0006238915,0.001029598,0.00105783,0.0007175981,0.0008548728,0.000901634,0.0006282823,0.001067248],"category_scores_gemma":[0.003160326,0.0004424044,0.0006495494,0.001830389,0.0003553117,0.0006590344,0.001176014,0.0007245406,0.0003730703],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005804944,"about_ca_system_score_gemma":0.001117777,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003943245,"about_ca_topic_score_gemma":0.005000906,"domain_scores_codex":[0.99824,0.0006183154,0.0002626815,0.0003259048,0.0003253843,0.0002278066],"domain_scores_gemma":[0.9958743,0.0002880597,0.002356393,0.0005383316,0.0003957785,0.0005469945],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002528372,0.0000736671,0.9987398,0.00001650242,0.00005648241,0.00004727142,0.0000339262,0.00003774874,0.00006288137,0.00001124378,0.0002359792,0.0004317257],"study_design_scores_gemma":[0.00006379862,0.0002393189,0.9988159,0.00001103461,0.00003473646,0.0002266184,0.00009799183,0.0002511389,0.0000372611,0.000008942587,0.0002084301,0.00000481577],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949538,0.000188419,0.0002566343,0.00004430141,0.00001012371,0.0002174528,0.003748721,0.000007700134,0.000572837],"genre_scores_gemma":[0.9873257,0.000154519,0.0007047022,0.000114407,0.00005695507,0.0005069631,0.01088464,0.000006030782,0.0002462658],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003943245,"threshold_uncertainty_score":0.01623827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1813065084311542,"score_gpt":0.5043529544761092,"score_spread":0.323046446044955,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}