{"id":"W4376225670","doi":"10.1096/fj.202300057r","title":"USP25 contributes to defective neurogenesis and cognitive impairments","year":2023,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Natural Science Foundation of China","keywords":"Neurogenesis; Hippocampus; Neuroscience; Neural stem cell; Neocortex; Biology; Psychology; Stem cell; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003782741,0.0000936751,0.00008334748,0.000048579,0.0002527605,0.00005406891,0.0001075664,0.0000448472,0.00001328787],"category_scores_gemma":[0.0001918093,0.00006527578,0.00005717744,0.0001341501,0.00005212188,0.000002476591,0.0001278927,0.00009843604,0.00005362502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006320661,"about_ca_system_score_gemma":0.00004045999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003618727,"about_ca_topic_score_gemma":0.00000446394,"domain_scores_codex":[0.9993311,0.0001222025,0.0001014847,0.0001379371,0.0000861802,0.0002211582],"domain_scores_gemma":[0.999628,0.00004753223,0.00004458044,0.00008663239,0.00008549466,0.0001077392],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001867724,0.00001757712,0.01015064,0.000004623574,0.0001365407,0.00003099856,0.0001957298,0.000009745143,0.981294,0.00002297359,0.001397811,0.006552632],"study_design_scores_gemma":[0.0006701779,0.0003998919,0.02971884,0.00002938784,0.00004786117,0.0002579342,0.0004599481,0.00001666414,0.9660373,0.0004034378,0.001854138,0.0001044565],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976538,0.0005431024,0.0007802345,0.00034142,0.0001212555,0.0002056633,0.00004977173,0.00001149968,0.0002932951],"genre_scores_gemma":[0.9983823,0.0001725894,0.00002098093,0.0009181453,0.0001738695,0.0000197525,0.00001376023,0.00001281139,0.0002858397],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0195682,"threshold_uncertainty_score":0.2661869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0145065565565244,"score_gpt":0.2608014729403157,"score_spread":0.2462949163837913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}