{"id":"W4376274404","doi":"10.3390/vaccines11050977","title":"Optimal Expression, Function, and Immunogenicity of an HIV-1 Vaccine Derived from the Approved Ebola Vaccine, rVSV-ZEBOV","year":2023,"lang":"en","type":"article","venue":"Vaccines","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Université Laval; Western University; National Research Council Canada","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Canada Foundation for Innovation","keywords":"Virology; Ebola vaccine; Ebola virus; Vesicular stomatitis virus; Immunogenicity; Biology; Ebolavirus; Antibody; Attenuated vaccine; Virus; Immunology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003866555,0.0002379916,0.0004336337,0.0001885775,0.0003036988,0.00005021628,0.0001875216,0.000138471,0.0004216091],"category_scores_gemma":[0.0002442188,0.0001474919,0.0001265422,0.0007245915,0.00002523885,0.0002204952,0.0002294393,0.0002932688,0.00006681374],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002050151,"about_ca_system_score_gemma":0.00006895039,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009061469,"about_ca_topic_score_gemma":0.000142295,"domain_scores_codex":[0.9983521,0.0001304383,0.0004602512,0.0004274627,0.0002786954,0.0003511097],"domain_scores_gemma":[0.9984897,0.0002470152,0.0001252584,0.0006351136,0.0003312891,0.0001716213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002658201,0.0002768473,0.08427172,0.00007107709,0.0002474739,0.00001404638,0.0003598893,0.000120361,0.8877658,0.00003731195,0.01610201,0.008075268],"study_design_scores_gemma":[0.004084296,0.0005429556,0.891315,0.00008293935,0.0001503759,0.00003176653,0.0007084011,0.003596366,0.09553035,0.0002291231,0.003550267,0.0001781969],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951988,0.000765905,0.0007044883,0.002217043,0.0002074654,0.0005243616,0.00006054421,0.0001953936,0.000126016],"genre_scores_gemma":[0.9973966,0.0002953387,0.0004451535,0.000180727,0.0004801046,0.00006525165,0.0002341708,0.00004362808,0.000858967],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8070433,"threshold_uncertainty_score":0.6014544,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01996700079320553,"score_gpt":0.2867426876378467,"score_spread":0.2667756868446412,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}