{"id":"W4376274404","doi":"10.3390/vaccines11050977","title":"Optimal Expression, Function, and Immunogenicity of an HIV-1 Vaccine Derived from the Approved Ebola Vaccine, rVSV-ZEBOV","year":2023,"lang":"en","type":"article","venue":"Vaccines","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Université Laval; Western University; National Research Council Canada","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Canada Foundation for Innovation","keywords":"Virology; Ebola vaccine; Ebola virus; Vesicular stomatitis virus; Immunogenicity; Biology; Ebolavirus; Antibody; Attenuated vaccine; Virus; Immunology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002294693,0.0002181524,0.0001690259,0.0001580129,0.0001501551,0.0004402282,0.0001446158,0.0002854352,0.0004468213],"category_scores_gemma":[0.000254822,0.0001380325,0.0001254592,0.0001240444,0.0001934582,0.0002914356,0.0001409967,0.0003765447,0.0002112878],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004418096,"about_ca_system_score_gemma":0.0002630918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003592652,"about_ca_topic_score_gemma":0.0005224892,"domain_scores_codex":[0.9998392,0.00003785234,0.00001387253,0.00002001662,0.00004643745,0.00004264031],"domain_scores_gemma":[0.9999361,0.00001428443,0.00001573982,0.000007644357,0.0000122804,0.00001395044],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008784984,0.00004001452,0.0003650358,0.00001665075,0.000003068607,0.0000148725,0.00001195597,0.0004087254,0.9977561,0.0002532599,0.00002434312,0.001018174],"study_design_scores_gemma":[0.00002245289,0.0004118073,0.003785851,0.00001144701,0.00001502954,0.0002023693,0.00003967423,0.00257324,0.9905131,0.0002207745,0.002199671,0.000004612143],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948397,0.0009217119,0.003218404,0.00006902832,0.000005977678,0.00002477381,0.0001042134,0.00001248731,0.0008036923],"genre_scores_gemma":[0.9958221,0.0004632042,0.002787819,0.0000236585,0.000004807383,0.00001554933,0.0002769408,0.00001069251,0.0005953434],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004468213,"threshold_uncertainty_score":0.003205538,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01996700079320553,"score_gpt":0.2867426876378467,"score_spread":0.2667756868446412,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}