{"id":"W4376609056","doi":"10.1007/s40257-023-00780-w","title":"Once-Daily Crisaborole Ointment, 2%, as a Long-Term Maintenance Treatment in Patients Aged ≥ 3 Months with Mild-to-Moderate Atopic Dermatitis: A 52-Week Clinical Study","year":2023,"lang":"en","type":"article","venue":"American Journal of Clinical Dermatology","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Barrie Urology Group","funders":"Pfizer","keywords":"Medicine; Atopic dermatitis; Clinical endpoint; Maintenance therapy; Adverse effect; Eczema Area and Severity Index; Double blind; Incidence (geometry); Randomized controlled trial; Placebo; Surgery; Internal medicine; Dermatology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001228139,0.0008588716,0.002400132,0.0003994539,0.0004582052,0.0006344314,0.0006151657,0.0009016512,0.002236973],"category_scores_gemma":[0.000617947,0.000466988,0.001746229,0.0003399999,0.0005546755,0.000680735,0.000282306,0.001905017,0.0005935042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004247271,"about_ca_system_score_gemma":0.000901114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001143184,"about_ca_topic_score_gemma":0.002790279,"domain_scores_codex":[0.9996748,0.0001242206,0.00002720097,0.00006025599,0.00004010517,0.00007343227],"domain_scores_gemma":[0.9994248,0.00008290927,0.00009694399,0.00004841159,0.0000552971,0.0002916059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7668785,0.1077873,0.009409813,0.001239204,0.001819181,0.0003862391,0.0003118276,0.0006816518,0.03732478,0.0000887261,0.001348439,0.07272428],"study_design_scores_gemma":[0.3053719,0.6590217,0.0317987,0.00004003485,0.0008938791,0.0001492249,0.00006247601,0.0004671035,0.001118267,0.00003147332,0.001016279,0.00002908087],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964073,0.001897133,0.0001144225,0.0001023668,0.00006648836,0.0006243515,0.0001853732,0.00002451264,0.0005779298],"genre_scores_gemma":[0.994306,0.002168608,0.0004606618,0.0005182481,0.0002266026,0.000725165,0.0004701041,0.000008304437,0.001116254],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002400132,"threshold_uncertainty_score":0.007483363,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04220595719627587,"score_gpt":0.3948880800747534,"score_spread":0.3526821228784776,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}