{"id":"W4376610600","doi":"10.1128/spectrum.01404-23","title":"Multiomics Reveals Symbionts, Pathogens, and Tissue-Specific Microbiome of Blacklegged Ticks (Ixodes scapularis) from a Lyme Disease Hot Spot in Southeastern Ontario, Canada","year":2023,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Vector-borne infectious diseases","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Queen's University; Government of Canada; Government of Ontario","keywords":"Ixodes scapularis; Biology; Borrelia; Borrelia burgdorferi; Lyme disease; Tick; Anaplasma phagocytophilum; Microbiology; Microbiome; Ixodidae; Anaplasma; Ixodes; Amblyomma americanum; Virology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002733227,0.0005444047,0.0009369864,0.0003798885,0.0001858789,0.00002550416,0.0004283067,0.0004644548,0.001034091],"category_scores_gemma":[0.00007121491,0.0005534032,0.0001431808,0.0004441065,0.0006111516,0.00007627183,0.0003202932,0.0004778917,0.0003740171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003972876,"about_ca_system_score_gemma":0.0006275104,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.6224178,"about_ca_topic_score_gemma":0.8940319,"domain_scores_codex":[0.9966227,0.0004449956,0.0008610323,0.001017897,0.00004371181,0.00100966],"domain_scores_gemma":[0.9984937,0.0002832274,0.0003196409,0.0007086802,0.0000644508,0.0001303432],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000476743,0.0001703746,0.2625686,0.00003234391,0.0002276904,0.0001586652,0.0005718296,0.000009660207,0.7323685,0.00007977392,0.003207959,0.0001279359],"study_design_scores_gemma":[0.004394422,0.000214554,0.8296747,0.0002136274,0.0002152546,0.0001836352,0.0005949177,0.000004885144,0.141822,0.0006493868,0.02100123,0.001031413],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869308,0.005885692,0.00001772732,0.0003662788,0.001074229,0.0006495382,0.00490388,0.0001355954,0.00003629499],"genre_scores_gemma":[0.994905,0.0002251938,0.00005135845,0.0001979861,0.00005585096,0.00003652572,0.003128625,0.00006263544,0.001336854],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5905464,"threshold_uncertainty_score":0.9998791,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009106450210082684,"score_gpt":0.2028349729942739,"score_spread":0.1937285227841913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}