{"id":"W4376611005","doi":"10.1158/1078-0432.c.6516061.v2","title":"Data from Safety and Efficacy of Axicabtagene Ciloleucel versus Standard of Care in Patients 65 Years of Age or Older with Relapsed/Refractory Large B-Cell Lymphoma","year":2023,"lang":"en","type":"preprint","venue":"","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Gilead Sciences","keywords":"Chemoimmunotherapy; Medicine; Internal medicine; Adverse effect; Clinical endpoint; Cytokine release syndrome; Refractory (planetary science); Oncology; Gastroenterology; Randomized controlled trial; Lymphoma; Surgery; Rituximab; Immunotherapy; Chimeric antigen receptor; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002138843,0.0004277209,0.001135273,0.0003346698,0.0002424586,0.0006904224,0.0004213371,0.0007641573,0.00291501],"category_scores_gemma":[0.002841877,0.0002151586,0.002190673,0.0004952925,0.0005427589,0.0005989507,0.0003221603,0.001089412,0.0003973877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006118118,"about_ca_system_score_gemma":0.0006642804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006808712,"about_ca_topic_score_gemma":0.001834724,"domain_scores_codex":[0.9988953,0.0006425375,0.0001237921,0.0001021681,0.000133448,0.0001026783],"domain_scores_gemma":[0.9975213,0.0009770377,0.000806886,0.000222149,0.0001013473,0.0003712601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9133152,0.003633339,0.02134779,0.001067675,0.003830912,0.0001606897,0.0001194523,0.0009374474,0.005611001,0.000119544,0.001834316,0.0480227],"study_design_scores_gemma":[0.442466,0.3533703,0.1785961,0.0003677539,0.01020454,0.0005978921,0.0002875245,0.001442985,0.005062958,0.0004701303,0.007053506,0.00008034388],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924753,0.003652573,0.0001344083,0.000321773,0.00005749842,0.0002795588,0.001533551,0.00001380432,0.001531481],"genre_scores_gemma":[0.9963632,0.001041216,0.0001298142,0.0004745817,0.00008839173,0.0002156917,0.001232646,0.000005597942,0.0004489091],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00291501,"threshold_uncertainty_score":0.01131141,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04952137718723923,"score_gpt":0.3293537248937822,"score_spread":0.279832347706543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}