{"id":"W4376612549","doi":"10.26434/chemrxiv-2023-cdlf8","title":"Flavonoids as dual-target inhibitors against α-glucosidase and α-amylase: a systematic review of in vitro studies","year":2023,"lang":"en","type":"review","venue":"ChemRxiv","topic":"Natural Antidiabetic Agents Studies","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"York University","keywords":"Acarbose; Amylase; Checklist; In vitro; Enzyme; Chemistry; Biochemistry; Traditional medicine; Biology; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001105632,0.0007402197,0.008483528,0.0004082873,0.00005997748,0.00001008457,0.000154706,0.0002705579,0.00001000102],"category_scores_gemma":[0.004649514,0.0004761763,0.0006835542,0.001169299,0.0002800574,0.00005189282,0.0004011639,0.0005999906,0.0001414155],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002263129,"about_ca_system_score_gemma":0.0002164666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005347893,"about_ca_topic_score_gemma":0.000001024228,"domain_scores_codex":[0.9960192,0.000238895,0.002148204,0.0006423371,0.000509246,0.0004420765],"domain_scores_gemma":[0.9973273,0.0007318601,0.0009359718,0.0006131404,0.0002375683,0.0001542036],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.000006776837,0.00006733932,0.000003439989,0.9914148,0.001305891,0.0002881272,0.000112695,4.746606e-9,0.00005153184,0.000008061197,0.001928146,0.004813117],"study_design_scores_gemma":[0.0004189902,0.00006347462,0.000001403407,0.9755149,0.004970307,0.0000593924,0.0001968821,6.205536e-7,0.0007112889,0.00002354776,0.01765353,0.0003856365],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005971449,0.9942132,1.132156e-7,0.0002342139,0.0002480048,0.004409895,0.0000174931,0.00008427161,0.0001956941],"genre_scores_gemma":[0.000086339,0.9971855,0.00009293934,0.0002905317,0.0001475812,0.0006654116,0.0001164635,0.00009733449,0.001317936],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01589995,"threshold_uncertainty_score":0.999769,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05243575798659547,"score_gpt":0.3599682007306123,"score_spread":0.3075324427440168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}