{"id":"W4376612756","doi":"10.1038/s41598-023-34363-w","title":"Behavioral and cellular responses to circadian disruption and prenatal immune activation in mice","year":2023,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research; Centre hospitalier universitaire Sainte-Justine; Natural Sciences and Engineering Research Council of Canada; Velux Stiftung","keywords":"Circadian rhythm; Offspring; Prepulse inhibition; Dentate gyrus; Immune system; Autism; Neuroscience; Pregnancy; Microglia; Physiology; Autism spectrum disorder; Medicine; Schizophrenia (object-oriented programming); Endocrinology; Immunology; Biology; Internal medicine; Hippocampus; Psychiatry; Inflammation; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003985828,0.0007788572,0.0003763895,0.001428412,0.0004254695,0.0005156391,0.0004985444,0.000907098,0.001794177],"category_scores_gemma":[0.0002240474,0.0004893249,0.000720884,0.000317043,0.0007875587,0.0003342674,0.0004909227,0.002281135,0.0004570693],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007859059,"about_ca_system_score_gemma":0.0005125446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002073539,"about_ca_topic_score_gemma":0.004861353,"domain_scores_codex":[0.9994212,0.00008238704,0.00006652209,0.0001772561,0.0001093154,0.0001432858],"domain_scores_gemma":[0.9994392,0.00004059575,0.000203486,0.00006036301,0.00003969777,0.0002166965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008590533,0.0005131733,0.00130871,0.00004426854,0.00001876138,0.0001598117,0.0001406991,0.0002119969,0.9941511,0.0001912037,0.0001627781,0.002238373],"study_design_scores_gemma":[0.0002259972,0.006638438,0.04674911,0.0000922474,0.000109531,0.0007697308,0.0004517111,0.003178071,0.9363061,0.0005632736,0.00485002,0.00006576386],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905745,0.0009886958,0.003501739,0.0003815679,0.00008002629,0.0001181757,0.002657609,0.0002729964,0.001424625],"genre_scores_gemma":[0.9750881,0.00192928,0.00913664,0.0005422151,0.00003654429,0.0009548347,0.002497786,0.0001529824,0.00966155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002073539,"threshold_uncertainty_score":0.006002188,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03149703426229176,"score_gpt":0.2893255591317349,"score_spread":0.2578285248694431,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}