{"id":"W4376616796","doi":"10.1097/hep.0000000000000458","title":"Future directions in acute liver failure","year":2023,"lang":"en","type":"review","venue":"Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":123,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Cancer Institute; Vagelos College of Physicians and Surgeons, Columbia University; Imperial College London; University of Alberta; Institut National de la Santé et de la Recherche Médicale; University of Texas Southwestern Medical Center; University of South Carolina; Virginia Commonwealth University; Medical School, University of Michigan; Université de Montréal; Northwestern University; Medical University of South Carolina; Southwestern Medical Foundation; University of Pennsylvania; University of Pittsburgh; National Institute of Diabetes and Digestive and Kidney Diseases; Johns Hopkins University; University of Southern California","keywords":"Medicine; Hepatic encephalopathy; Cirrhosis; Liver disease; Liver injury; Liver failure; Gastroenterology; Internal medicine; Natural history; Encephalopathy; Intensive care medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004947962,0.0008609823,0.001570008,0.001303519,0.0008288362,0.003337965,0.001553761,0.004135221,0.02109545],"category_scores_gemma":[0.01069656,0.000269114,0.001250327,0.001150349,0.001684357,0.005242242,0.001866851,0.007682172,0.007047019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001759916,"about_ca_system_score_gemma":0.005542532,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001523058,"about_ca_topic_score_gemma":0.003363537,"domain_scores_codex":[0.9980782,0.0008204883,0.0002333984,0.000238706,0.0003911932,0.0002379473],"domain_scores_gemma":[0.989689,0.004673898,0.0005409388,0.0003551589,0.00316221,0.001578749],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002172577,0.0001616988,0.0008543609,0.004707786,0.0000895456,0.0003512495,0.0002712142,0.0002432395,0.000270918,0.02259306,0.2455134,0.7247263],"study_design_scores_gemma":[0.00007518405,0.0001702982,0.0008274242,0.005849756,0.0000786843,0.0005339359,0.0003825437,0.0001713192,0.00008546038,0.01589138,0.9759036,0.00003052031],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004688349,0.8691835,0.00192312,0.0942894,0.01985156,0.00004756449,0.0001585291,0.000181694,0.01389589],"genre_scores_gemma":[0.007743591,0.8979988,0.004823856,0.04744675,0.03432389,0.0001890211,0.0004154803,0.00005781687,0.0070008],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02109545,"threshold_uncertainty_score":0.0705713,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2274488840532966,"score_gpt":0.4755329614212113,"score_spread":0.2480840773679147,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}