{"id":"W4376617354","doi":"10.1158/1078-0432.c.6571946.v2","title":"Data from Treatment of Prostate Cancer with CD46-targeted &lt;sup&gt;225&lt;/sup&gt;Ac Alpha Particle Radioimmunotherapy","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of California, San Francisco; U.S. Department of Defense; U.S. Department of Energy; University of California, Davis; University of Alberta; DOD Prostate Cancer Research Program; School of Veterinary Medicine, University of California, Davis","keywords":"Radioimmunotherapy; DOTA; Prostate cancer; Biodistribution; DU145; Cancer research; Cancer; Medicine; Chemistry; Antibody; Nuclear medicine; Internal medicine; Immunology; LNCaP; Monoclonal antibody; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001827913,0.0007518253,0.001385252,0.0007429137,0.0003523634,0.0006756947,0.0005338633,0.0006984703,0.01161157],"category_scores_gemma":[0.001463188,0.0001843624,0.001330081,0.001067104,0.0003785076,0.0003918706,0.0002941307,0.001399124,0.003281632],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007916696,"about_ca_system_score_gemma":0.001046393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001920964,"about_ca_topic_score_gemma":0.002100745,"domain_scores_codex":[0.9986181,0.0003991071,0.0002450527,0.0001179261,0.0004949799,0.0001249138],"domain_scores_gemma":[0.9980181,0.0007342281,0.0003101877,0.0002964948,0.0004186577,0.0002222512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.08520504,0.007244717,0.01044074,0.01094064,0.003466955,0.0007944845,0.0002861915,0.002564662,0.2942238,0.0012334,0.0511247,0.5324746],"study_design_scores_gemma":[0.006833689,0.09296759,0.06464388,0.0009364292,0.00578952,0.004453395,0.0002280502,0.001021334,0.4418445,0.0006312657,0.3805136,0.0001367216],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"dataset","genre_scores_codex":[0.5513732,0.2233039,0.01704355,0.004774846,0.002550689,0.00335726,0.08834171,0.001451066,0.1078039],"genre_scores_gemma":[0.8065782,0.07875598,0.006048358,0.004375509,0.0006168307,0.002090671,0.06723701,0.0003138644,0.03398367],"genre_candidate":"dataset","genre_consensus":null,"teacher_disagreement_score":0.01161157,"threshold_uncertainty_score":0.03884459,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1042069740246789,"score_gpt":0.3760119135621262,"score_spread":0.2718049395374473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}