{"id":"W4376642613","doi":"10.1080/07391102.2023.2213339","title":"Rational design of B-cell and T-cell multi epitope-based vaccine against Zika virus, an <i>in silico</i> study","year":2023,"lang":"en","type":"article","venue":"Journal of Biomolecular Structure and Dynamics","topic":"vaccines and immunoinformatics approaches","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Epitope; Adjuvant; Virology; Zika virus; Biology; Docking (animal); Antigen; Immune system; CTL*; Virus; Immunology; Medicine; CD8","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003304752,0.000173435,0.0002709964,0.0001774157,0.0000489961,0.00003566722,0.0001510886,0.0001243881,0.000001293531],"category_scores_gemma":[0.00002631218,0.000142522,0.00005977251,0.000193095,0.00002633946,0.00001695092,0.00006653665,0.0001261012,1.442876e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001108196,"about_ca_system_score_gemma":0.00008987787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008969664,"about_ca_topic_score_gemma":0.00003765748,"domain_scores_codex":[0.9989443,0.00008878353,0.0004944116,0.0001591658,0.0001572292,0.000156082],"domain_scores_gemma":[0.9992907,0.00001645729,0.0003065443,0.0001891038,0.0001180308,0.00007916494],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002196649,0.0002318184,0.006290797,0.00006039715,0.00004231442,0.00002047659,0.0001584933,0.006517641,0.9848275,0.000006842169,0.00003055701,0.001593561],"study_design_scores_gemma":[0.01118552,0.004028623,0.02639004,0.00004730088,0.0001353319,0.00009077435,0.001714652,0.3376353,0.6179804,0.0001328809,0.0001261359,0.0005330932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9765508,0.0007147529,0.02236689,0.00003591638,0.00005867587,0.0002249914,0.00003720172,0.00000295675,0.000007870125],"genre_scores_gemma":[0.992171,0.0003919974,0.007164124,0.00009791135,0.00003534186,0.000001569772,0.0001092942,0.00001860859,0.00001012571],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3668471,"threshold_uncertainty_score":0.5811877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009244991732708801,"score_gpt":0.234696592693648,"score_spread":0.2254516009609392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}