{"id":"W4376643273","doi":"10.3390/cancers15082251","title":"Role of Secreted Frizzled-Related Protein 1 in Early Breast Carcinogenesis and Breast Cancer Aggressiveness","year":2023,"lang":"en","type":"article","venue":"Cancers","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Occupational Cancer Research Centre","funders":"Fonds de Recherche du Québec - Santé; Fondation du cancer du sein du Québec","keywords":"Carcinogenesis; Breast cancer; Cancer research; Transcriptome; Organoid; Biology; Cancer; Medicine; Internal medicine; Oncology; Gene expression; Gene; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001180795,0.0002017696,0.0002476455,0.0003830085,0.000172501,0.0002798201,0.00008324609,0.0001640457,0.001054281],"category_scores_gemma":[0.0001593077,0.00009449884,0.0001986712,0.0003189478,0.0001150847,0.0001159976,0.0001523659,0.0002174663,0.0002627238],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002123712,"about_ca_system_score_gemma":0.0001747183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001525338,"about_ca_topic_score_gemma":0.002066855,"domain_scores_codex":[0.9998696,0.00001400378,0.000008077256,0.00004439687,0.00003265986,0.00003121167],"domain_scores_gemma":[0.999899,0.00001482268,0.00003810685,0.000009239349,0.00001560364,0.00002313796],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003353323,0.00001426459,0.01442535,0.00007782227,0.00002262055,0.0001019386,0.00005992788,0.00006823373,0.9798017,0.00004516154,0.00009440522,0.004953346],"study_design_scores_gemma":[0.00001489782,0.0002620609,0.6175247,0.00001765135,0.00008318423,0.001208328,0.0001542967,0.0007382535,0.374892,0.0001170783,0.00497193,0.00001564353],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920713,0.004149262,0.001212771,0.0000737711,0.000007884293,0.000012691,0.001818761,0.00004134551,0.0006121119],"genre_scores_gemma":[0.9942188,0.001193154,0.001109236,0.000045172,0.000005566356,0.00001508849,0.001983457,0.000007568086,0.001421966],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001525338,"threshold_uncertainty_score":0.003526926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009692229416886206,"score_gpt":0.2491551891121038,"score_spread":0.2394629596952176,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}