{"id":"W4376643458","doi":"10.1038/s41598-023-34255-z","title":"Circular mitochondrial-encoded mRNAs are a distinct subpopulation of mitochondrial mRNA in Trypanosoma brucei","year":2023,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Circular RNAs in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; University of Minnesota","keywords":"Trypanosoma brucei; Messenger RNA; Biology; Mitochondrial DNA; Mitochondrion; Virology; Genetics; Gene; Molecular biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002922411,0.0002249906,0.0003156123,0.0003182243,0.0001453596,0.0001075963,0.0002723612,0.0002008736,0.00003361973],"category_scores_gemma":[0.001383402,0.0002369564,0.0002774394,0.001010291,0.0002678253,0.00001632639,0.0001931236,0.0001011419,0.00002126393],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004561161,"about_ca_system_score_gemma":0.0002409307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009466738,"about_ca_topic_score_gemma":0.0002897719,"domain_scores_codex":[0.9968872,0.0001253045,0.0008154296,0.001097873,0.0006523021,0.0004218984],"domain_scores_gemma":[0.9976977,0.00001934113,0.0005486382,0.0013948,0.000206441,0.0001330615],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004707328,0.0001026865,0.0825767,0.00005817762,0.00002805845,0.0003719738,0.00006173168,0.0003758376,0.9082375,0.00001038147,0.00787427,0.0002556313],"study_design_scores_gemma":[0.001116814,0.0000802459,0.2743644,0.0001776377,0.00006904812,0.0001952812,0.0002082109,0.0003767738,0.7034515,0.004495798,0.01484879,0.0006154862],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905858,0.0003620385,0.0002256923,0.0000601756,0.007912992,0.000530644,0.00002608365,0.00005199652,0.0002445612],"genre_scores_gemma":[0.9975009,0.000009585822,0.0002184286,0.00001162483,0.0003771629,0.00006214693,0.0008999439,0.00003731691,0.0008829],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.204786,"threshold_uncertainty_score":0.9662803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01478706507051887,"score_gpt":0.2611820029850835,"score_spread":0.2463949379145647,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}