{"id":"W4376645308","doi":"10.3390/ijms24108803","title":"Calcium Homeostasis, Transporters, and Blockers in Health and Diseases of the Cardiovascular System","year":2023,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Calcium; Homeostasis; Calcium metabolism; Cell biology; Calcium in biology; Intracellular; Extracellular; Second messenger system; Secretion; Calcium signaling; Biology; Transporter; Chemistry; Endocrinology; Internal medicine; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005875458,0.000113571,0.0004077344,0.000209921,0.00003812847,0.00002475807,0.0002950452,0.00007203707,5.3131e-7],"category_scores_gemma":[0.00005406759,0.00007391003,0.0003428831,0.0001836742,0.0001838848,0.00000667166,0.00006060114,0.00008123105,1.363179e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003234887,"about_ca_system_score_gemma":0.0003698918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002283327,"about_ca_topic_score_gemma":0.000003391513,"domain_scores_codex":[0.9986053,0.0001603051,0.0004937814,0.0001755008,0.000474373,0.0000907164],"domain_scores_gemma":[0.999275,0.00001612432,0.0004413697,0.00009466593,0.0001070056,0.00006587364],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008118756,0.0001010092,0.00140808,0.01049733,0.002657633,0.0001352091,0.0003452394,0.001572049,0.0001708078,0.001017462,0.0004667204,0.9815473],"study_design_scores_gemma":[0.001443663,0.0006352547,0.00104089,0.02197729,0.0005995209,0.001508009,0.001574314,0.0002415188,0.0004487031,0.00009676309,0.9699049,0.0005291619],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003351283,0.9951197,0.0004265064,0.0001798176,0.0007453249,0.0001363307,0.00003293056,0.000001772082,0.000006330885],"genre_scores_gemma":[0.03440351,0.9653297,0.00006829199,0.0000338817,0.0001273774,0.000003239586,0.00001247128,0.000009337722,0.00001218927],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9810181,"threshold_uncertainty_score":0.3013963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03683763610584587,"score_gpt":0.3192910601426318,"score_spread":0.2824534240367859,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}