{"id":"W4376871925","doi":"10.1097/ede.0000000000001628","title":"The Prevalent New-user Design for Studies With no Active Comparator: The Example of Statins and Cancer","year":2023,"lang":"en","type":"article","venue":"Epidemiology","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Hazard ratio; Medicine; Propensity score matching; Confidence interval; Statin; Incidence (geometry); Cohort; Observational study; Context (archaeology); Cohort study; Cancer; Proportional hazards model; Randomized controlled trial; Internal medicine; Oncology; Mathematics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.2809994,0.001198998,0.002302362,0.001703299,0.001585991,0.003116029,0.002926988,0.004251826,0.007696419],"category_scores_gemma":[0.3677482,0.001039227,0.008479564,0.001805579,0.003824794,0.002963077,0.003316933,0.005214048,0.0007720204],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001550874,"about_ca_system_score_gemma":0.002780868,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00125145,"about_ca_topic_score_gemma":0.001570274,"domain_scores_codex":[0.5457854,0.4246435,0.01090979,0.009644177,0.008279509,0.0007375913],"domain_scores_gemma":[0.5908265,0.3007594,0.03047295,0.06530364,0.01045101,0.002186487],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.05199885,0.001591895,0.1292849,0.01403461,0.02855455,0.001250822,0.004399627,0.02912338,0.005823508,0.3936727,0.02825323,0.3120119],"study_design_scores_gemma":[0.03460527,0.03114762,0.09096172,0.008706922,0.02778299,0.003474379,0.001004683,0.1442406,0.01121865,0.473767,0.1719224,0.001167796],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.1074611,0.009975247,0.8383196,0.01234355,0.006995976,0.01122713,0.002454997,0.0009274603,0.01029496],"genre_scores_gemma":[0.4818442,0.001646514,0.4854098,0.007920062,0.001358203,0.01848412,0.0006580527,0.0002204404,0.002458612],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.2809994,"threshold_uncertainty_score":0.8866557,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1335027919705891,"score_gpt":0.3862941338376331,"score_spread":0.2527913418670439,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}