{"id":"W4376875424","doi":"10.3390/cells12101401","title":"Ginsentide TP1 Protects Hypoxia-Induced Dysfunction and ER Stress-Linked Apoptosis","year":2023,"lang":"en","type":"article","venue":"Cells","topic":"Ginseng Biological Effects and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Regional Municipality of Niagara; Brock University","funders":"Ministry of Education, India; Nanyang Technological University","keywords":"Endothelial dysfunction; Hypoxia (environmental); Oxidative stress; Endothelium; Endothelial activation; Cell biology; Unfolded protein response; Nitric oxide; Signal transduction; Pharmacology; Biology; Medicine; Cancer research; Endoplasmic reticulum; Endocrinology; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001025949,0.0001144276,0.0000943852,0.00003042938,0.0001062894,0.00002635863,0.00007819415,0.0001476341,0.0000152959],"category_scores_gemma":[0.00004153708,0.00009278811,0.00004627097,0.000134642,0.0000450925,0.000002607359,0.00008324142,0.00007652313,0.0001046475],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004943562,"about_ca_system_score_gemma":0.00001398305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000162302,"about_ca_topic_score_gemma":0.000004022279,"domain_scores_codex":[0.9992784,0.00003941763,0.0001037122,0.0003206806,0.00006172718,0.0001960133],"domain_scores_gemma":[0.9996083,0.00002110897,0.00004020323,0.0002230404,0.00003145734,0.00007589832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001178066,0.00002701516,0.00009002852,0.0000191284,0.00001462349,6.310889e-7,0.000007327786,0.00002690504,0.9933282,0.00005476971,0.002209842,0.00420972],"study_design_scores_gemma":[0.0002770302,0.0001696447,0.007921842,0.000009051438,0.00001018807,0.000001193494,0.00002932226,0.0001156651,0.9670996,0.0001256533,0.02409744,0.0001433472],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982629,0.0000501846,0.0002573647,0.0003724802,0.0001200011,0.0003700698,0.00002148956,0.00005971165,0.0004857731],"genre_scores_gemma":[0.9976487,0.0001331143,0.0001400872,0.0002094812,0.000159995,0.0001124701,0.0001456202,0.00001391769,0.001436664],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0262286,"threshold_uncertainty_score":0.378379,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01722840029042684,"score_gpt":0.2447258248858896,"score_spread":0.2274974245954628,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}