{"id":"W4376954750","doi":"10.1016/j.acthis.2023.152045","title":"KCCs, NKCCs, and NCC: Potential targets for cardiovascular therapeutics? A comprehensive review of cell and region specific expression and function","year":2023,"lang":"en","type":"review","venue":"Acta Histochemica","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"The Scarborough Hospital; Krembil Foundation; University of Toronto","funders":"","keywords":"Internal medicine; Homeostasis; Endocrinology; Depolarization; Cardiomyopathy; Biology; Heart failure; Cell biology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006552387,0.0009511449,0.001663425,0.001801415,0.0002457361,0.001160931,0.00096344,0.00107006,0.003053221],"category_scores_gemma":[0.0007108807,0.0003186618,0.000399404,0.002072182,0.0005849801,0.001560093,0.0007160874,0.001748423,0.001958809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005854219,"about_ca_system_score_gemma":0.001226517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001059237,"about_ca_topic_score_gemma":0.002129955,"domain_scores_codex":[0.9998478,0.00001927687,0.00002684158,0.00002879951,0.00005833645,0.00001903114],"domain_scores_gemma":[0.9997314,0.0001154251,0.00003636303,0.000008700269,0.00007982319,0.00002833498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001905713,0.00005896912,0.0001587685,0.01520627,0.00007000498,0.0001791784,0.00004596936,0.0003201463,0.005472338,0.003458749,0.03320693,0.9416322],"study_design_scores_gemma":[0.00003000185,0.000147137,0.0008431743,0.00285654,0.0001644999,0.001046717,0.00007076137,0.0001189327,0.001160352,0.001941293,0.9915888,0.00003177803],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008117565,0.9991055,0.0001250208,0.0001743328,0.0001455833,0.00000230715,0.00001925854,0.000005064762,0.0003417364],"genre_scores_gemma":[0.000331437,0.9988047,0.0001876695,0.0001345269,0.0001350922,0.000004108672,0.00002870654,0.000001114125,0.0003726587],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003053221,"threshold_uncertainty_score":0.01021403,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04124284094410354,"score_gpt":0.2710288052977478,"score_spread":0.2297859643536442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}