{"id":"W4377008656","doi":"10.1177/20417314231172574","title":"Non-hypertrophic chondrogenesis of mesenchymal stem cells through mechano-hypoxia programing","year":2023,"lang":"en","type":"article","venue":"Journal of Tissue Engineering","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Faculty of Medicine and Dentistry, University of Alberta; Canada Foundation for Innovation; University of Alberta; Canadian Institutes of Health Research; Alberta Cancer Foundation; Natural Sciences and Engineering Research Council of Canada; Government of Alberta; Cliff Lede Family Charitable Foundation; Women and Children's Health Research Institute; Children's Health Research Institute","keywords":"Chondrogenesis; Mesenchymal stem cell; Cartilage; Osteoarthritis; Cartilage oligomeric matrix protein; Tissue engineering; Hyaline cartilage; Cell biology; Stem cell; Chemistry; Biomedical engineering; Pathology; Immunology; Medicine; Biology; Anatomy; Articular cartilage","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002047799,0.0001838396,0.0005404886,0.0002774577,0.00003065302,0.00001373077,0.0001056906,0.0001010838,0.00002945535],"category_scores_gemma":[0.00001865194,0.0001567436,0.000190031,0.0004500897,0.00001243682,0.0001554922,0.00003600271,0.0001792634,0.00002755503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000057065,"about_ca_system_score_gemma":0.00005675031,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003456211,"about_ca_topic_score_gemma":4.515417e-7,"domain_scores_codex":[0.9986652,0.000009866903,0.0004931115,0.0001291028,0.0004011671,0.0003015472],"domain_scores_gemma":[0.9993142,0.00004150146,0.000203141,0.0001713764,0.000131023,0.0001387332],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004554593,0.00006951568,0.0001417087,0.0002382389,0.0001312045,0.0008360567,0.0004247895,0.001082267,0.9805392,0.00007702554,0.00009140449,0.01632307],"study_design_scores_gemma":[0.00185287,0.00211849,0.0002910501,0.0006516363,0.0002384058,0.0006535446,0.0002539969,0.0008338317,0.9892306,0.00002172038,0.003703787,0.0001501217],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954832,0.001441055,0.001544683,0.0001255117,0.0009959668,0.0002833816,0.000004038197,0.00006550909,0.00005670921],"genre_scores_gemma":[0.9865342,0.0002171389,0.0121017,0.000009663852,0.0003666364,0.000008460443,0.000002829511,0.00005346651,0.0007058569],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01617295,"threshold_uncertainty_score":0.6391819,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01567958096192024,"score_gpt":0.2493562994660578,"score_spread":0.2336767185041375,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}