{"id":"W4377008656","doi":"10.1177/20417314231172574","title":"Non-hypertrophic chondrogenesis of mesenchymal stem cells through mechano-hypoxia programing","year":2023,"lang":"en","type":"article","venue":"Journal of Tissue Engineering","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Faculty of Medicine and Dentistry, University of Alberta; Canada Foundation for Innovation; University of Alberta; Canadian Institutes of Health Research; Alberta Cancer Foundation; Natural Sciences and Engineering Research Council of Canada; Government of Alberta; Cliff Lede Family Charitable Foundation; Women and Children's Health Research Institute; Children's Health Research Institute","keywords":"Chondrogenesis; Mesenchymal stem cell; Cartilage; Osteoarthritis; Cartilage oligomeric matrix protein; Tissue engineering; Hyaline cartilage; Cell biology; Stem cell; Chemistry; Biomedical engineering; Pathology; Immunology; Medicine; Biology; Anatomy; Articular cartilage","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001348794,0.0002441176,0.0001330254,0.0001267482,0.00007853946,0.0001673745,0.000122503,0.0001387843,0.0008241378],"category_scores_gemma":[0.00006322667,0.00007421015,0.0001375693,0.00007999175,0.0001451421,0.0001537649,0.0001602703,0.0002166795,0.0001420397],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001142259,"about_ca_system_score_gemma":0.0001996794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003138252,"about_ca_topic_score_gemma":0.0009848173,"domain_scores_codex":[0.9999249,0.000009949435,0.000007764503,0.00001066841,0.00003497152,0.00001185113],"domain_scores_gemma":[0.9999585,0.000006474426,0.00001248485,0.000004100071,0.00000968009,0.000008742973],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002011848,0.00001708435,0.00008587542,0.00006337555,0.000001786982,0.00002353209,0.00001047366,0.00004871514,0.9969728,0.0001043902,0.00002427083,0.002627613],"study_design_scores_gemma":[0.000006863404,0.0001637828,0.001668148,0.000008219591,0.000008132683,0.00007652683,0.00001326531,0.0005333177,0.9949412,0.00003319053,0.002545049,0.000002294298],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9775906,0.003628502,0.01539486,0.00009978361,0.00007298291,0.00009738162,0.0001859707,0.00007819977,0.002851722],"genre_scores_gemma":[0.9888234,0.002039227,0.005142281,0.00007580948,0.00002469866,0.00008718863,0.0002252422,0.00001373324,0.003568419],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008241378,"threshold_uncertainty_score":0.002756953,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01567958096192024,"score_gpt":0.2493562994660578,"score_spread":0.2336767185041375,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}