{"id":"W4377010934","doi":"10.1038/s41598-023-34985-0","title":"Indel driven rapid evolution of core nuclear pore protein gene promoters","year":2023,"lang":"en","type":"article","venue":"Scientific Reports","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Winnipeg","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Natural Sciences and Engineering Research Council of Canada","keywords":"Promoter; Indel; Biology; Gene; Genetics; Nuclear pore; Gene expression; Regulatory sequence; Regulation of gene expression; Homeobox; Cytoplasm","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001808975,0.0002304456,0.0002223034,0.0003561725,0.000152683,0.0003475141,0.0002771557,0.0003287535,0.001294018],"category_scores_gemma":[0.0006359039,0.0002252292,0.0002613777,0.0001957283,0.000309177,0.0002541067,0.0005434044,0.0009242403,0.0006238692],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002458284,"about_ca_system_score_gemma":0.0001374188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001963533,"about_ca_topic_score_gemma":0.0004389754,"domain_scores_codex":[0.999838,0.00001690659,0.00001142652,0.00005916475,0.00005002787,0.0000243898],"domain_scores_gemma":[0.9994143,0.0001862488,0.0001777238,0.00008524687,0.00006845481,0.00006793284],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004847351,0.00001341621,0.0008808517,0.00002522853,0.000006602353,0.0001864047,0.00002775742,0.0002385015,0.9957699,0.0001972284,0.00002429821,0.002581295],"study_design_scores_gemma":[0.00001894537,0.0001688075,0.03032075,0.00002091964,0.0000333024,0.00212884,0.00007694852,0.006537958,0.9549951,0.0008830322,0.004785768,0.0000296807],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834825,0.0005568277,0.01349248,0.00006408583,0.00002777115,0.00002641673,0.0003600004,0.0002925922,0.001697297],"genre_scores_gemma":[0.9888934,0.0004252574,0.006905899,0.00009732017,0.00001672666,0.00003482078,0.0008497301,0.0002091703,0.002567519],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001294018,"threshold_uncertainty_score":0.004328907,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01765369585764011,"score_gpt":0.2620605618542061,"score_spread":0.244406865996566,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}