{"id":"W4377011344","doi":"10.2217/nnm-2022-0237","title":"Novel Delivery of Sorafenib by Natural Killer Cell-Derived Exosomes-Enhanced Apoptosis in Triple-Negative Breast Cancer","year":2023,"lang":"en","type":"article","venue":"Nanomedicine","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Propidium iodide; Cytotoxic T cell; Microvesicles; Cancer research; Acridine orange; Apoptosis; Annexin; Population; Chemistry; Biology; Molecular biology; Programmed cell death; Medicine; microRNA; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001140915,0.0001898893,0.0002642149,0.000110694,0.0001036701,0.0002729503,0.0001102354,0.0002139897,0.0004477013],"category_scores_gemma":[0.00008528768,0.00006545958,0.0002132705,0.00006982674,0.0001078554,0.0002529405,0.0001706287,0.0001983222,0.0001426629],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002473849,"about_ca_system_score_gemma":0.0001620121,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002527025,"about_ca_topic_score_gemma":0.0004041079,"domain_scores_codex":[0.9999187,0.00001265385,0.000006087791,0.00001777674,0.0000233635,0.00002143313],"domain_scores_gemma":[0.9999686,0.000004646125,0.000008939316,0.000002655844,0.000006926509,0.000008240037],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00018078,0.00003604279,0.0002174652,0.0001138441,0.000007578715,0.0001128295,0.00002463027,0.0001734288,0.9943038,0.00009793617,0.00005412047,0.004677617],"study_design_scores_gemma":[0.00004185426,0.000547333,0.001892694,0.000007739144,0.00002192955,0.0004729234,0.00003356266,0.001929405,0.9922171,0.00004061299,0.002789263,0.000005600913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926053,0.002239155,0.004239609,0.00008847916,0.00003026218,0.00003995377,0.0001081257,0.00004511331,0.000603957],"genre_scores_gemma":[0.9961461,0.0008475945,0.002011469,0.00002130884,0.000005616334,0.00002698153,0.00007877766,0.000007182921,0.0008550487],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004477013,"threshold_uncertainty_score":0.001794934,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00694249936865108,"score_gpt":0.2472309717739347,"score_spread":0.2402884724052836,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}