{"id":"W4377014201","doi":"10.20944/preprints202305.1347.v1","title":"Amyloid ß&lt;sub&gt;1–42&lt;/sub&gt; Peptide Induces Galectin-1&lt;sup&gt;S8&lt;/sup&gt; O-GlcNAcylation to Lead Microglia Migration","year":2023,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Galectins and Cancer Biology","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Université de Montréal","keywords":"Microglia; Peptide; Chemistry; Cell biology; Amyloid (mycology); P3 peptide; Amyloid precursor protein; Biochemistry; Biology; Alzheimer's disease; Inflammation; Immunology; Internal medicine; Medicine; Disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000094159,0.0003155341,0.0001614519,0.0001886066,0.00009128763,0.0002506703,0.00009660602,0.0002285975,0.00194272],"category_scores_gemma":[0.0000677362,0.0001008405,0.0002433551,0.0001281518,0.0001747892,0.0001367215,0.0001684451,0.0005994304,0.0007518998],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001674521,"about_ca_system_score_gemma":0.0001350626,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003885255,"about_ca_topic_score_gemma":0.0004544279,"domain_scores_codex":[0.9998798,0.00001613807,0.00001065341,0.00002429042,0.00002670757,0.00004240699],"domain_scores_gemma":[0.9999441,0.000007166126,0.00001437775,0.000007683901,0.000005922243,0.00002066557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000123923,0.0000344215,0.00009527131,0.00001975641,0.000003689918,0.00003756562,0.00001114855,0.00002799374,0.9988425,0.00005940178,0.00008361765,0.0006606486],"study_design_scores_gemma":[0.000015843,0.0002050628,0.003330333,0.000004321179,0.000005992702,0.0001580699,0.00002862941,0.0004591897,0.9936649,0.0000961285,0.0020282,0.000003258219],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935962,0.0006964951,0.001888832,0.0001778301,0.00007085189,0.00002641527,0.0005592331,0.00008951754,0.00289467],"genre_scores_gemma":[0.990411,0.0005942907,0.001870717,0.0001833741,0.00002492058,0.00003133005,0.001011849,0.00005828847,0.005814163],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00194272,"threshold_uncertainty_score":0.006499052,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06830195760947129,"score_gpt":0.3059376579924276,"score_spread":0.2376357003829563,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}