{"id":"W4377077831","doi":"10.1007/978-1-0716-3056-3_3","title":"Three-Dimensional Spheroids for Cancer Research","year":2023,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"3D Printing in Biomedical Research","field":"Engineering","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Trinity College","funders":"","keywords":"Cancer; Cancer cell; Spheroid; In vivo; Cell culture; 3D cell culture; Computational biology; Cancer research; Biology; Biotechnology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006588513,0.0003894371,0.0005954065,0.000539129,0.0003372118,0.001348277,0.0004978079,0.0009253906,0.002927733],"category_scores_gemma":[0.0004543787,0.0004140895,0.0006987832,0.0006158401,0.0005784745,0.0007608993,0.0009519599,0.001332433,0.002479061],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005709711,"about_ca_system_score_gemma":0.0003746772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006016447,"about_ca_topic_score_gemma":0.001121424,"domain_scores_codex":[0.9996,0.0001074935,0.00003636557,0.00005686777,0.000172044,0.00002727239],"domain_scores_gemma":[0.9995981,0.0001417691,0.00004780415,0.0001176537,0.00004475721,0.00004992871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001132833,0.00006771312,0.0001892481,0.0004869973,0.00003072565,0.0002233303,0.00017474,0.004006871,0.9369085,0.01960615,0.005281106,0.03291136],"study_design_scores_gemma":[0.00006267914,0.0001782993,0.000957105,0.0001118417,0.00004654135,0.0008389519,0.00008299045,0.01671751,0.8328589,0.01157679,0.1364824,0.00008602731],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.1110699,0.056452,0.7820649,0.004324097,0.003326537,0.0004034962,0.005564302,0.004815403,0.03197939],"genre_scores_gemma":[0.5125788,0.03909362,0.4187021,0.001429471,0.0003606811,0.0007626392,0.004821646,0.001112095,0.02113886],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.002927733,"threshold_uncertainty_score":0.009794176,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.119765099620137,"score_gpt":0.5201833580307899,"score_spread":0.4004182584106528,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}