{"id":"W4377097120","doi":"10.1186/s10194-023-01594-1","title":"The comparative effectiveness of migraine preventive drugs: a systematic review and network meta-analysis","year":2023,"lang":"en","type":"review","venue":"The Journal of Headache and Pain","topic":"Migraine and Headache Studies","field":"Medicine","cited_by":133,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Impact","funders":"H. Lundbeck A/S; Bundesministerium für Bildung und Forschung; Amgen; Pfizer; European Stroke Organisation; Teva Pharmaceutical Industries; AstraZeneca; Allergan; Eli Lilly and Company","keywords":"Medicine; Gabapentin; Discontinuation; Migraine; Topiramate; Placebo; Meta-analysis; Adverse effect; Randomized controlled trial; Internal medicine; Epilepsy; Psychiatry; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03589646,0.00342491,0.02311789,0.0107296,0.0006788613,0.003607615,0.002693855,0.002689177,0.004549002],"category_scores_gemma":[0.0852525,0.001801609,0.04268284,0.009458494,0.0009958233,0.002408764,0.001982039,0.002048988,0.0003135265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003861373,"about_ca_system_score_gemma":0.003568867,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006927752,"about_ca_topic_score_gemma":0.01007065,"domain_scores_codex":[0.9604664,0.02643032,0.006881906,0.002785486,0.002832893,0.0006029353],"domain_scores_gemma":[0.936181,0.05227386,0.007206691,0.001592214,0.002317181,0.0004290563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001779651,0.00001958729,0.002864875,0.1854616,0.8025085,0.0000821906,0.00004620356,0.0008415242,0.00007501167,0.0001872667,0.000407818,0.005725776],"study_design_scores_gemma":[0.0009009858,0.000160817,0.001865171,0.01407484,0.981223,0.00005964696,0.00002324438,0.0004353577,0.00005680469,0.0003943871,0.0007853818,0.0000202825],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007511527,0.9867989,0.002384163,0.0004802854,0.0002822448,0.0009561326,0.001045287,0.00005788071,0.0004835383],"genre_scores_gemma":[0.3902429,0.5896422,0.01045218,0.001543246,0.0005782245,0.005057563,0.001909237,0.00007775338,0.0004967598],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.03589646,"threshold_uncertainty_score":0.1898409,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1660497188525566,"score_gpt":0.4203865134532218,"score_spread":0.2543367946006652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}