{"id":"W4377104328","doi":"10.3390/cells12101417","title":"Immunomodulatory Macrophages Enable E-MNC Therapy for Radiation-Induced Salivary Gland Hypofunction","year":2023,"lang":"en","type":"article","venue":"Cells","topic":"Salivary Gland Disorders and Functions","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Japan Society for the Promotion of Science; Japan Agency for Medical Research and Development","keywords":"Integrin alpha M; Macrophage; Peripheral blood mononuclear cell; CD68; Inflammation; In vivo; Phagocytosis; Fibrosis; Immune system; Immunohistochemistry; Immunology; Biology; Medicine; In vitro; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000186099,0.0003115132,0.0002886417,0.0002035861,0.00009564758,0.0001885625,0.000135954,0.0003247391,0.0007219011],"category_scores_gemma":[0.00008594785,0.00007353459,0.0002746856,0.00009395585,0.000148102,0.0001470565,0.0002359393,0.0004393013,0.0001994851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007961255,"about_ca_system_score_gemma":0.0001604601,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001165335,"about_ca_topic_score_gemma":0.0002444052,"domain_scores_codex":[0.999895,0.00002390136,0.000009350665,0.00002061621,0.00002350551,0.00002775922],"domain_scores_gemma":[0.9999639,0.000004836889,0.00001068622,0.000005476556,0.000005070081,0.000009982024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002461964,0.0001176829,0.0002816132,0.00009784145,0.000007197907,0.00007895933,0.00002107737,0.00007807031,0.9938036,0.0001123199,0.00005154526,0.005103903],"study_design_scores_gemma":[0.00009830597,0.001782554,0.003580148,0.00002259123,0.00006132266,0.0005589344,0.00004483562,0.0008098075,0.9842128,0.00007697544,0.008746325,0.00000536059],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859414,0.004945917,0.007370452,0.0001196261,0.00007537071,0.0001514884,0.0001434306,0.00009971465,0.001152614],"genre_scores_gemma":[0.9900234,0.002031812,0.00579932,0.00009123531,0.00002659945,0.0001407673,0.0001785,0.00001148852,0.001696932],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007219011,"threshold_uncertainty_score":0.002415001,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02855392435522067,"score_gpt":0.2749993614429502,"score_spread":0.2464454370877295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}