{"id":"W4377104328","doi":"10.3390/cells12101417","title":"Immunomodulatory Macrophages Enable E-MNC Therapy for Radiation-Induced Salivary Gland Hypofunction","year":2023,"lang":"en","type":"article","venue":"Cells","topic":"Salivary Gland Disorders and Functions","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Japan Society for the Promotion of Science; Japan Agency for Medical Research and Development","keywords":"Integrin alpha M; Macrophage; Peripheral blood mononuclear cell; CD68; Inflammation; In vivo; Phagocytosis; Fibrosis; Immune system; Immunohistochemistry; Immunology; Biology; Medicine; In vitro; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001617872,0.0001337739,0.0001923355,0.0001491302,0.0001917816,0.0000290584,0.0000506773,0.0001012631,0.0003598846],"category_scores_gemma":[0.00003036125,0.0001117538,0.0001321792,0.0003032066,0.00002005468,0.00009268543,0.00001256662,0.00008576617,0.0003729835],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003245876,"about_ca_system_score_gemma":0.00008179895,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006560008,"about_ca_topic_score_gemma":0.000001591905,"domain_scores_codex":[0.9991683,0.00002022314,0.0001815071,0.000241027,0.0001316468,0.0002572711],"domain_scores_gemma":[0.9993953,0.0001224465,0.00004991127,0.0002743879,0.00007150495,0.00008641106],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00152083,0.0004761733,0.01913676,0.000162917,0.0003622509,0.00003213986,0.0006679276,0.0001800513,0.5994028,0.0002745613,0.3198583,0.05792531],"study_design_scores_gemma":[0.01768774,0.002212234,0.2589089,0.0000643957,0.0002262586,0.0000344273,0.0009813078,0.003361902,0.1704115,0.003364777,0.5420548,0.0006917759],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883813,0.001778595,0.0005308968,0.0006073817,0.001987636,0.0008674446,0.00003485017,0.000320588,0.005491363],"genre_scores_gemma":[0.987016,0.0009089292,0.0001449414,0.0007852283,0.0006435371,0.0001335058,0.0003663773,0.00004330384,0.009958182],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4289913,"threshold_uncertainty_score":0.4794073,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02855392435522067,"score_gpt":0.2749993614429502,"score_spread":0.2464454370877295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}