{"id":"W4377192892","doi":"10.1007/s40123-023-00724-x","title":"Development of Novel Patient-Reported Outcome (PRO) and Observer-Reported Outcome (ObsRO) Instruments in Retinitis Pigmentosa (RP) and Leber Congenital Amaurosis (LCA): ViSIO-PRO and ViSIO-ObsRO","year":2023,"lang":"en","type":"article","venue":"Ophthalmology and Therapy","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Novartis Pharma","keywords":"Retinitis pigmentosa; Medicine; Amaurosis; Outcome (game theory); Ophthalmology; Optometry; Retinal","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.08525666,0.0005134876,0.0006538701,0.002560245,0.001148955,0.002962571,0.001319694,0.0008756345,0.002525802],"category_scores_gemma":[0.1078932,0.0003807083,0.001841153,0.002191849,0.002407364,0.003573617,0.004267096,0.001698586,0.0004132562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00362184,"about_ca_system_score_gemma":0.009877145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001264762,"about_ca_topic_score_gemma":0.003195109,"domain_scores_codex":[0.9578299,0.03259885,0.004045678,0.001117658,0.003532504,0.0008754299],"domain_scores_gemma":[0.8801153,0.0901242,0.01226547,0.00329407,0.01288233,0.001318666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009692869,0.0006619232,0.08953906,0.02271748,0.0003579109,0.0006996111,0.2165561,0.001187172,0.004718466,0.0221413,0.00820589,0.632246],"study_design_scores_gemma":[0.0007594422,0.004370308,0.2066238,0.04655654,0.001462908,0.002559212,0.4275711,0.006108199,0.01339935,0.05477929,0.2350697,0.0007401569],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.780414,0.01100329,0.1391006,0.01413937,0.0008109508,0.01632807,0.005083595,0.0002936508,0.03282641],"genre_scores_gemma":[0.7792151,0.004541358,0.1842964,0.001863721,0.0001071545,0.02597983,0.001946911,0.00009645071,0.001952981],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08525666,"threshold_uncertainty_score":0.4508857,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07608534800620578,"score_gpt":0.3166253994141432,"score_spread":0.2405400514079374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}