{"id":"W4377195778","doi":"10.1111/bjh.18863","title":"Granulocyte transfusion during cord blood transplant for relapsed, refractory <scp>AML</scp> is associated with massive <scp>CD8</scp><sup>+</sup> T‐cell expansion, significant cytokine release syndrome and induction of disease remission","year":2023,"lang":"en","type":"article","venue":"British Journal of Haematology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Children's Cancer and Leukaemia Group","keywords":"Medicine; Cytokine release syndrome; Internal medicine; Immunology; Hematopoietic stem cell transplantation; Gastroenterology; Transplantation; T cell; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005151004,0.0001771575,0.0004265385,0.00008480733,0.0001302504,0.0002821683,0.0002114246,0.0002081257,0.0006333083],"category_scores_gemma":[0.0009153704,0.00007014763,0.0001876762,0.0001326281,0.0002794757,0.0001626885,0.0001424915,0.0006372246,0.0001233344],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003256015,"about_ca_system_score_gemma":0.0002894345,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003863648,"about_ca_topic_score_gemma":0.000712664,"domain_scores_codex":[0.9997428,0.0001315747,0.00002754956,0.00002253858,0.00004365112,0.00003192478],"domain_scores_gemma":[0.9995139,0.0001281323,0.0001960693,0.00004481148,0.00001499657,0.0001020411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"case_report","study_design_scores_codex":[0.1477905,0.007318432,0.102059,0.001207622,0.0008269257,0.007492288,0.0007714321,0.004403159,0.2539424,0.0009821939,0.006861992,0.4663441],"study_design_scores_gemma":[0.02123761,0.3430126,0.4077195,0.0002836262,0.001078985,0.03199838,0.0003270728,0.01885905,0.1650255,0.0008489616,0.009545285,0.00006346675],"study_design_candidate":"case_report","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989581,0.0004370486,0.0002352333,0.00005051188,0.00001389004,0.00003282366,0.00002569444,0.00002141797,0.0002251874],"genre_scores_gemma":[0.9994161,0.0001382133,0.0002027444,0.00005187552,0.00001746016,0.00001598193,0.00007323894,0.000003442729,0.00008091896],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006333083,"threshold_uncertainty_score":0.002724171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01542665138166101,"score_gpt":0.2495936100112106,"score_spread":0.2341669586295496,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}