{"id":"W4377564734","doi":"10.4049/immunohorizons.2200089","title":"SRF617 Is a Potent Inhibitor of CD39 with Immunomodulatory and Antitumor Properties","year":2023,"lang":"en","type":"article","venue":"ImmunoHorizons","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Pharmacology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001565996,0.0004860633,0.0004119331,0.0003246085,0.0001797474,0.00018503,0.0002673324,0.0004466746,0.001417286],"category_scores_gemma":[0.0001151283,0.0001230475,0.0003050777,0.0002319771,0.0001373727,0.000134534,0.0001071889,0.0005418683,0.0006816851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002704492,"about_ca_system_score_gemma":0.0002850457,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003917201,"about_ca_topic_score_gemma":0.000750132,"domain_scores_codex":[0.9998453,0.00002090469,0.0000130744,0.00001995012,0.00005343696,0.0000473595],"domain_scores_gemma":[0.9999408,0.000009031639,0.00001178123,0.000005388745,0.00001005897,0.00002298462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006032135,0.0004821995,0.0002905783,0.0001443597,0.00002544181,0.0002883791,0.00002113882,0.0003092868,0.9707515,0.0002989297,0.001163296,0.02562168],"study_design_scores_gemma":[0.0007651451,0.005979549,0.00390941,0.00001989014,0.00006288377,0.002337034,0.00001818904,0.002003451,0.9442387,0.0001466879,0.04050039,0.00001858837],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9630474,0.0223222,0.00451585,0.0005960597,0.0002025878,0.0002669402,0.000764108,0.0004370329,0.007847837],"genre_scores_gemma":[0.9774916,0.008131349,0.00535278,0.0002478745,0.00009732711,0.0002241396,0.002149118,0.00003217559,0.0062736],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001417286,"threshold_uncertainty_score":0.004741251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01078199735626016,"score_gpt":0.214037487548942,"score_spread":0.2032554901926819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}