{"id":"W4377564734","doi":"10.4049/immunohorizons.2200089","title":"SRF617 Is a Potent Inhibitor of CD39 with Immunomodulatory and Antitumor Properties","year":2023,"lang":"en","type":"article","venue":"ImmunoHorizons","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Pharmacology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009518007,0.0001274621,0.0001454206,0.0000577522,0.00008347213,0.00001590974,0.0001052464,0.00006590823,0.000009103505],"category_scores_gemma":[0.00001620653,0.00009786426,0.00004739151,0.0001343813,0.0001300677,0.000005358391,0.0001207631,0.00006347589,0.00001035418],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004539959,"about_ca_system_score_gemma":0.00006628007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000476167,"about_ca_topic_score_gemma":0.000001338825,"domain_scores_codex":[0.999302,0.00002055854,0.0001659309,0.0002179295,0.0001083145,0.0001852449],"domain_scores_gemma":[0.9995509,0.000005106054,0.00006304521,0.0002762932,0.00007015876,0.00003452849],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001288087,0.0000315324,0.002635688,0.00004050356,0.0001133659,0.000008765786,0.0001799485,0.00003445856,0.9921369,0.00004412105,0.004089635,0.0005562806],"study_design_scores_gemma":[0.0008023946,0.0009929101,0.009082789,0.0001149787,0.00004282199,0.00005955488,0.0004942241,0.00007087778,0.9726271,0.00002194296,0.01541233,0.0002780497],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921824,0.00700046,0.00004390502,0.0001831606,0.00008273496,0.0001278608,0.00001614937,0.00002313336,0.0003401844],"genre_scores_gemma":[0.9981557,0.0004143757,0.0001237411,0.00005007285,0.0001088447,0.00001700835,0.00002834589,0.000023127,0.001078754],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01950977,"threshold_uncertainty_score":0.3990789,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01078199735626016,"score_gpt":0.214037487548942,"score_spread":0.2032554901926819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}