{"id":"W4377693677","doi":"10.1093/ecco-jcc/jjad089","title":"Early intervention with biologic therapy in Crohn´s disease: how early is early?","year":2023,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Crohn's disease; Intervention (counseling); Medicine; Disease; Internal medicine; Psychiatry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005588327,0.0003967985,0.001956898,0.0007285668,0.0005232797,0.00251772,0.0007107452,0.001504459,0.001950869],"category_scores_gemma":[0.02059701,0.000261628,0.0008790545,0.0009711393,0.0008268365,0.002525157,0.0006851488,0.001648191,0.0004089127],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008811254,"about_ca_system_score_gemma":0.001757874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00103199,"about_ca_topic_score_gemma":0.001494181,"domain_scores_codex":[0.9961205,0.001884914,0.0005441065,0.0003555435,0.0006728254,0.0004220472],"domain_scores_gemma":[0.9829803,0.008106972,0.005870605,0.0003268507,0.00126332,0.001451949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01299551,0.002109769,0.4858249,0.007434878,0.0007313963,0.0008962472,0.001015401,0.0005475275,0.001173871,0.001204514,0.00611862,0.4799473],"study_design_scores_gemma":[0.003384619,0.01710098,0.8479202,0.03476432,0.004302258,0.009479814,0.004401268,0.002332043,0.002903559,0.01034992,0.06276719,0.000293819],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.4541876,0.511314,0.002628017,0.02484834,0.001637604,0.0001743406,0.0004439124,0.00004661942,0.004719467],"genre_scores_gemma":[0.900795,0.08782362,0.004061215,0.003641241,0.002676286,0.0001347604,0.0002967648,0.00002064871,0.0005505632],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.005588327,"threshold_uncertainty_score":0.02955425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01016238524934614,"score_gpt":0.2452705395632495,"score_spread":0.2351081543139034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}