{"id":"W4377695422","doi":"10.1016/j.clim.2023.109391","title":"Extracellular vesicles derived from the intestinal microbiota of patients with CGD-associated inflammatory bowel disease have pro-inflammatory effects","year":2023,"lang":"en","type":"article","venue":"Clinical Immunology","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"","keywords":"Chronic granulomatous disease; Inflammatory bowel disease; Immunology; Inflammation; Medicine; Biology; Internal medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005248746,0.0003226178,0.0003641698,0.00004826373,0.0001419393,0.00002269633,0.0007269984,0.0003678223,0.00002291485],"category_scores_gemma":[0.00267565,0.0002473809,0.0002664862,0.0001301517,0.001295881,0.00001067826,0.000531253,0.0004044559,0.00007758928],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002581933,"about_ca_system_score_gemma":0.000262798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000110765,"about_ca_topic_score_gemma":0.00001873956,"domain_scores_codex":[0.9970743,0.000776069,0.000818625,0.0006575534,0.0001949239,0.0004785214],"domain_scores_gemma":[0.9973124,0.0006723215,0.0005170143,0.001063546,0.000253326,0.0001814308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001205153,0.000458853,0.6045289,0.00003862242,0.000487672,0.00007199699,0.00004898157,0.00003078008,0.3913959,0.00002514923,0.0007574891,0.0009505675],"study_design_scores_gemma":[0.002676679,0.0004823942,0.9467734,0.0001287204,0.0002010833,8.312031e-7,0.00005990617,0.0001278015,0.04820963,0.0001723391,0.000862663,0.0003045384],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994889,0.003566326,0.0001170348,0.0001606189,0.0003506006,0.0007083553,0.000119414,0.00007501888,0.00001362773],"genre_scores_gemma":[0.9979304,0.0001637955,0.0001735349,0.0001359012,0.000152701,0.00007040073,0.0010897,0.00006876138,0.0002147688],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3431862,"threshold_uncertainty_score":0.9999979,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0112847134121341,"score_gpt":0.2580168920641442,"score_spread":0.2467321786520101,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}