{"id":"W4377819809","doi":"10.7554/elife.78335.sa2","title":"Author response: Gene and protein expression and metabolic flux analysis reveals metabolic scaling in liver ex vivo and in vivo","year":2023,"lang":"en","type":"peer-review","venue":"","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"In vivo; Flux (metallurgy); Metabolic flux analysis; Metabolic pathway; Ex vivo; Gene expression; Scaling; Biology; Cytosol; Proteomics; Metabolism; Computational biology; Cell biology; Chemistry; Biochemistry; Gene; Enzyme; Genetics; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002098156,0.0004635546,0.0006609981,0.00114589,0.0007247967,0.002012987,0.0005326374,0.00136637,0.1675463],"category_scores_gemma":[0.01526044,0.0001810625,0.0002573642,0.001216361,0.0008881942,0.001028506,0.0011606,0.001057854,0.07780513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000610256,"about_ca_system_score_gemma":0.001716055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009703859,"about_ca_topic_score_gemma":0.002365622,"domain_scores_codex":[0.9983009,0.0002739112,0.000112744,0.0003681671,0.000812587,0.000131839],"domain_scores_gemma":[0.9858006,0.002557139,0.0008464499,0.0007977855,0.008291915,0.001706059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001166947,0.0001150396,0.006429113,0.001661322,0.0000584345,0.0009444652,0.0006110939,0.0008252047,0.06432519,0.00373245,0.7417719,0.1783589],"study_design_scores_gemma":[0.0001314429,0.0003167707,0.02702507,0.0002268588,0.00003744021,0.0008760146,0.001744422,0.001238558,0.02484756,0.002960411,0.9405059,0.00008961026],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"commentary","genre_scores_codex":[0.1446131,0.01376973,0.02976056,0.2346875,0.1357314,0.001702768,0.03037123,0.007878305,0.4014854],"genre_scores_gemma":[0.2302403,0.007683486,0.01033142,0.01088827,0.0109557,0.0003827663,0.008462388,0.001978175,0.7190774],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.1675463,"threshold_uncertainty_score":0.5604982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04732927350153276,"score_gpt":0.3469094183268985,"score_spread":0.2995801448253657,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}