{"id":"W4377940798","doi":"10.26508/lsa.202302133","title":"The CHARGE syndrome-associated protein FAM172A controls AGO2 nuclear import","year":2023,"lang":"en","type":"article","venue":"Life Science Alliance","topic":"Congenital Ear and Nasal Anomalies","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Université du Québec à Montréal","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Government of Canada; Fonds de Recherche du Québec - Santé; Université du Québec à Montréal","keywords":"Chromatin; Importin; Biology; Genetics; Cell biology; RNA-binding protein; RNA splicing; Mutation; Nuclear export signal; Nuclear transport; RNA; Gene; Cell nucleus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001573507,0.0003548285,0.0001944303,0.0004213153,0.0001990375,0.0003476223,0.0002205222,0.0002874177,0.002406608],"category_scores_gemma":[0.0003855939,0.0001451129,0.0002119343,0.0001685174,0.0003915296,0.0001927792,0.0004378314,0.0002605094,0.0006390711],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002782978,"about_ca_system_score_gemma":0.0002296039,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006701046,"about_ca_topic_score_gemma":0.0009546994,"domain_scores_codex":[0.9998127,0.00003703263,0.00001743329,0.00005435937,0.00004263015,0.00003584872],"domain_scores_gemma":[0.9997657,0.00004832282,0.00006276704,0.00003302214,0.00002344831,0.00006670438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001332382,0.000005541907,0.003361932,0.00001857145,0.000007498257,0.0007677527,0.00003011803,0.00008019496,0.9938056,0.0002792336,0.00006582285,0.001444375],"study_design_scores_gemma":[0.00003639877,0.00009858223,0.04768094,0.00001331588,0.00002569759,0.0054241,0.0001266829,0.003411664,0.9372389,0.0005536962,0.005374905,0.00001507889],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993725,0.0008285681,0.003218474,0.00007820601,0.00003327368,0.000006204031,0.0003102952,0.0001326693,0.001667285],"genre_scores_gemma":[0.9984937,0.0001258621,0.0005560933,0.00001429704,0.000004221882,0.000004249617,0.0001311757,0.00002677766,0.0006436594],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002406608,"threshold_uncertainty_score":0.008050859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01967028726529769,"score_gpt":0.2682866176189911,"score_spread":0.2486163303536935,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}