{"id":"W4377967869","doi":"10.1101/2023.05.22.541797","title":"Wired together, change together: Spike timing modifies transmission in converging assemblies","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Neural dynamics and brain function","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Azrieli Foundation; Israel Science Foundation; United States-Israel Binational Science Foundation; Rosetrees Trust; International Development Research Centre","keywords":"Postsynaptic potential; Neuroscience; Optogenetics; Neurotransmission; Inhibitory postsynaptic potential; Spike-timing-dependent plasticity; Spike (software development); Biology; Stimulation; Excitatory postsynaptic potential; Computer science; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000158492,0.0001752315,0.0002347402,0.0002068415,0.000189801,0.0005962722,0.000401971,0.0002715769,0.001449657],"category_scores_gemma":[0.000628888,0.0002203161,0.0001781082,0.0001193757,0.0004246656,0.0006836476,0.0005652895,0.0004895458,0.0002362815],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000266454,"about_ca_system_score_gemma":0.0001244004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002407317,"about_ca_topic_score_gemma":0.0002919579,"domain_scores_codex":[0.9998988,0.00001111025,0.000008174327,0.0000279815,0.00003409733,0.00001975941],"domain_scores_gemma":[0.9997994,0.00003768238,0.00005640839,0.00004101689,0.00002122942,0.0000443286],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008299323,0.00003742868,0.0008067347,0.00002101265,0.00002022128,0.0001222061,0.00005103667,0.002406161,0.9883704,0.001942845,0.0001070454,0.006031827],"study_design_scores_gemma":[0.00006963879,0.0005110365,0.03658955,0.00002919732,0.00008764408,0.0007152814,0.0002005525,0.1312073,0.814237,0.01344947,0.00285808,0.00004524932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827514,0.00008903753,0.01546032,0.00007486808,0.00003713591,0.000008199749,0.00004486581,0.0001893779,0.001344697],"genre_scores_gemma":[0.9945445,0.00005942072,0.004753533,0.00002476381,0.000007953141,0.000008817793,0.00003398332,0.00004301454,0.0005239903],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001449657,"threshold_uncertainty_score":0.004849553,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07609311588670223,"score_gpt":0.264592661970269,"score_spread":0.1884995460835668,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}