{"id":"W4377968793","doi":"10.1093/jsxmed/qdad061.110","title":"(114) Vaginal/Vulvar Symptoms with Lasofoxifene versus Fulvestrant in ESR1-mutated, ER+/HER2- Metastatic Breast Cancer Patients","year":2023,"lang":"en","type":"article","venue":"The Journal of Sexual Medicine","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Breast cancer; Fulvestrant; Oncology; Internal medicine; Population; Gynecology; Cancer; Estrogen receptor","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008343795,0.0004511712,0.001492852,0.0002739101,0.0002593493,0.0005469567,0.0003340973,0.000695001,0.003173285],"category_scores_gemma":[0.001085261,0.0002707209,0.001288844,0.0002751141,0.0003315086,0.0004041211,0.0002337361,0.0009021857,0.0002682063],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005586447,"about_ca_system_score_gemma":0.0006895271,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001105868,"about_ca_topic_score_gemma":0.002994935,"domain_scores_codex":[0.9996319,0.0001617151,0.00003463469,0.00006185451,0.00002771283,0.00008205825],"domain_scores_gemma":[0.9994299,0.000188384,0.0001168321,0.00002626178,0.00002955881,0.0002090359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.9363667,0.007845797,0.01155513,0.00040638,0.0008440667,0.00007930955,0.00008401616,0.0005551511,0.006359209,0.00006235988,0.0006684636,0.0351734],"study_design_scores_gemma":[0.3358109,0.5991194,0.05747505,0.00007271466,0.001624501,0.000202849,0.0001639205,0.0009239005,0.002449238,0.0001835966,0.001939976,0.00003395431],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970642,0.001465636,0.00005852327,0.00009820385,0.00005392856,0.0003446499,0.0003646527,0.00001421915,0.0005360299],"genre_scores_gemma":[0.9972605,0.000667661,0.0002313209,0.0001964461,0.00007347223,0.0004784816,0.0003598784,0.000002585017,0.0007297117],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003173285,"threshold_uncertainty_score":0.01061571,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01011242966031446,"score_gpt":0.2736181838117117,"score_spread":0.2635057541513972,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}