{"id":"W4377981728","doi":"10.1016/j.biopha.2023.114922","title":"Royal jelly mediates fibrotic signaling, collagen cross-linking and cell proliferation in cardiac fibroblasts","year":2023,"lang":"en","type":"article","venue":"Biomedicine & Pharmacotherapy","topic":"Bee Products Chemical Analysis","field":"Agricultural and Biological Sciences","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Moncton","funders":"Deanship of Research, Jordan University of Science and Technology; Deanship of Scientific Research, King Saud University; Jordan University of Science and Technology; King Saud University; Université de Moncton","keywords":"CTGF; Cell growth; Apoptosis; Royal jelly; Cardiac fibrosis; Signal transduction; Periostin; Fibrosis; Biology; Chemistry; Cell biology; Internal medicine; Biochemistry; Extracellular matrix; Medicine; Growth factor; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000218059,0.0003631711,0.0002271592,0.0002112802,0.000132881,0.0002586628,0.0001140822,0.0002736285,0.001170055],"category_scores_gemma":[0.0001804133,0.0001482049,0.0003616864,0.00009435692,0.0002141326,0.0002831927,0.0002037133,0.0004479254,0.0002522271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001370407,"about_ca_system_score_gemma":0.000113352,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003582783,"about_ca_topic_score_gemma":0.0005682389,"domain_scores_codex":[0.9998381,0.00004173115,0.00001736306,0.00003235262,0.00003770724,0.0000326556],"domain_scores_gemma":[0.9998772,0.00003172532,0.00004204915,0.00001086754,0.00001459752,0.00002361514],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008038277,0.000015858,0.00004934094,0.00006652143,0.00000400583,0.0000266014,0.00001887864,0.00001998763,0.9988004,0.00002490211,0.00001869892,0.0008743373],"study_design_scores_gemma":[0.00002686073,0.0007267821,0.004984472,0.00001651449,0.00002701183,0.0001960678,0.00005912696,0.0004503276,0.9908299,0.00004254115,0.002633309,0.000006999153],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874839,0.007553313,0.002541075,0.000154791,0.00004774057,0.00003485853,0.0001714507,0.0000427774,0.001970131],"genre_scores_gemma":[0.9928195,0.002620365,0.001864811,0.00009418721,0.00002467192,0.00004071446,0.0002167431,0.00001147412,0.002307564],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001170055,"threshold_uncertainty_score":0.003914297,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01484272257745098,"score_gpt":0.2630924356777186,"score_spread":0.2482497131002676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}