{"id":"W4378072258","doi":"10.3389/fendo.2023.1171886","title":"Efficacy of combination therapy with GABA, a DPP-4i and a PPI as an adjunct to insulin therapy in patients with type 1 diabetes","year":2023,"lang":"en","type":"article","venue":"Frontiers in Endocrinology","topic":"Diabetes Management and Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kelowna General Hospital","funders":"Novo Nordisk Fonden; Vetenskapsrådet; Novo Nordisk","keywords":"Medicine; Glycemic; Insulin; Internal medicine; Type 2 diabetes; Hypoglycemia; Diabetes mellitus; Gastroenterology; Endocrinology; Combination therapy; Dipeptidyl peptidase-4 inhibitor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001284658,0.0001336532,0.0003422233,0.0008259995,0.00002209373,0.000008801763,0.0001137127,0.00004958684,0.00002096581],"category_scores_gemma":[0.00005483384,0.00009307441,0.00001503711,0.0009467093,0.0001430372,0.00007741705,0.00004630516,0.0001664211,0.00001101389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003635699,"about_ca_system_score_gemma":0.00004153595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003422748,"about_ca_topic_score_gemma":0.00002115268,"domain_scores_codex":[0.9988036,0.00009360809,0.0001696185,0.0002863215,0.0002307421,0.00041609],"domain_scores_gemma":[0.9995224,0.00004649086,0.00004496486,0.000223266,0.00009154709,0.00007134021],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003201754,0.0006714677,0.878388,0.00002556209,0.00009665774,0.00002150783,0.0004331513,0.00001429737,0.00008516668,0.00009667345,0.0006742045,0.1162915],"study_design_scores_gemma":[0.0153719,0.009774979,0.9721277,0.00006652122,0.000007886013,2.408745e-7,0.0001809552,0.0001896269,0.000473139,0.0002358567,0.001464952,0.0001061894],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975124,0.0002840794,0.000009098766,0.0005245665,0.0001387936,0.001086121,0.000002237289,0.0000338866,0.0004088116],"genre_scores_gemma":[0.9983078,0.0004904886,0.0004559664,0.000204491,0.00001432837,0.00005942376,0.00006398156,0.00002427034,0.0003792336],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1161854,"threshold_uncertainty_score":0.3795464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01404636333776626,"score_gpt":0.2725522339436301,"score_spread":0.2585058706058638,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}