{"id":"W4378172813","doi":"10.1210/endocr/bqad081","title":"Regulation of Alternative Splicing by Steroid Hormones","year":2023,"lang":"en","type":"review","venue":"Endocrinology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Banting and Best Diabetes Centre, University of Toronto; Novo Nordisk; Natural Sciences and Engineering Research Council of Canada; Amgen","keywords":"RNA splicing; Alternative splicing; Biology; Minigene; Hormone; Steroid hormone; Exon; Splicing factor; Cell biology; Gene; Genetics; Endocrinology; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003305968,0.0007144521,0.0008348671,0.001530724,0.0002342651,0.000751078,0.0006241153,0.0006920103,0.002249629],"category_scores_gemma":[0.0003697946,0.000224597,0.0002831203,0.00161061,0.0004545618,0.0008798233,0.0005400049,0.001100541,0.002164091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005152821,"about_ca_system_score_gemma":0.0006642146,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005776151,"about_ca_topic_score_gemma":0.0007475843,"domain_scores_codex":[0.9998609,0.00002035362,0.00002078616,0.00003191397,0.00005081202,0.00001532336],"domain_scores_gemma":[0.9998538,0.00006685394,0.00002096833,0.000005651341,0.00003712518,0.00001554148],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006116533,0.00004031712,0.0001868484,0.01059544,0.00005036282,0.0003406369,0.00006560468,0.0004690945,0.006326345,0.007427847,0.02116742,0.953269],"study_design_scores_gemma":[0.000009100177,0.00005049561,0.0007938482,0.001359673,0.00003922616,0.001600461,0.00003945578,0.00009333719,0.0015177,0.00300559,0.9914738,0.00001722611],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001960221,0.997235,0.000335765,0.0002229606,0.0002179636,0.000004064542,0.00002210238,0.00001325983,0.001752962],"genre_scores_gemma":[0.0007863842,0.9980702,0.0002380562,0.0001340905,0.000131231,0.000006559028,0.00003401333,0.000002188473,0.0005973869],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002249629,"threshold_uncertainty_score":0.007525742,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05015017443692454,"score_gpt":0.359579044011904,"score_spread":0.3094288695749795,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}