{"id":"W4378194435","doi":"10.1007/978-3-031-26078-0_11","title":"Newly Approved Anti-parasitic Drugs for Malaria, Fascioliasis, Onchocerciasis, Chagas Disease, and African Trypanosomiasis","year":2023,"lang":"en","type":"book-chapter","venue":"Emerging infectious diseases of the 21st century","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Onchocerciasis; Malaria; Chagas disease; Trypanosomiasis; Parasitic disease; Ivermectin; Primaquine; Virology; African trypanosomiasis; Medicine; Filariasis; Immunology; Disease; Biology; Veterinary medicine; Helminths; Internal medicine; Chloroquine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00005177969,0.0006487757,0.001013787,0.0005032237,0.0005282842,0.00008620696,0.0004580338,0.0002785733,0.0001787431],"category_scores_gemma":[0.0007329672,0.0005339997,0.001044702,0.0002812091,0.0005849431,0.0001232743,0.0003207779,0.0005400581,0.00004309615],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002993571,"about_ca_system_score_gemma":0.0006512716,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009012347,"about_ca_topic_score_gemma":0.00002409531,"domain_scores_codex":[0.9967964,0.00006043998,0.0007034351,0.0008769311,0.0008124148,0.000750352],"domain_scores_gemma":[0.9965127,0.0003856901,0.0004985155,0.001351842,0.0003836762,0.0008675901],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"observational","study_design_scores_codex":[0.004187668,0.00415834,0.05018517,0.01934844,0.01502979,0.0001098268,0.002098231,0.0001884182,0.006905573,0.6069604,0.1344495,0.1563787],"study_design_scores_gemma":[0.005934652,0.0005914301,0.686058,0.002501876,0.006516058,0.00004826444,0.0006821884,0.00021983,0.000178241,0.01416717,0.2815428,0.001559432],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.1021054,0.08496945,0.0003977024,0.06080824,0.0127218,0.0437154,0.04919348,0.004880896,0.6412076],"genre_scores_gemma":[0.8573546,0.02533715,0.00009660177,0.0007415795,0.001755406,0.0007247976,0.001230467,0.0005384913,0.1122209],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.7552492,"threshold_uncertainty_score":0.9997112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01516163008331269,"score_gpt":0.2673966401539736,"score_spread":0.252235010070661,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}