{"id":"W4378194435","doi":"10.1007/978-3-031-26078-0_11","title":"Newly Approved Anti-parasitic Drugs for Malaria, Fascioliasis, Onchocerciasis, Chagas Disease, and African Trypanosomiasis","year":2023,"lang":"en","type":"book-chapter","venue":"Emerging infectious diseases of the 21st century","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Onchocerciasis; Malaria; Chagas disease; Trypanosomiasis; Parasitic disease; Ivermectin; Primaquine; Virology; African trypanosomiasis; Medicine; Filariasis; Immunology; Disease; Biology; Veterinary medicine; Helminths; Internal medicine; Chloroquine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002254518,0.0005143883,0.0002916057,0.0007231182,0.0003461513,0.001135524,0.0004640434,0.0006869278,0.03181993],"category_scores_gemma":[0.0002646639,0.0001389897,0.0002210603,0.0005993907,0.0004751282,0.001271902,0.0004451454,0.001679672,0.008007198],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006686781,"about_ca_system_score_gemma":0.0007333226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009833664,"about_ca_topic_score_gemma":0.0057655,"domain_scores_codex":[0.9999068,0.00001932584,0.000005412433,0.00001063631,0.00004896681,0.000008942387],"domain_scores_gemma":[0.9998962,0.00005295226,0.00001144931,0.000004569054,0.0000229635,0.00001188883],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005777735,0.00007854962,0.00009709236,0.001230949,0.000009157009,0.0002297321,0.0002073972,0.0002601835,0.00422634,0.08723637,0.4344775,0.471889],"study_design_scores_gemma":[0.000003361469,0.00001764131,0.00008942813,0.0001363771,0.000002543416,0.0002174145,0.00001947909,0.0000404502,0.000224881,0.00315631,0.9960897,0.000002387401],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001089573,0.5156898,0.003037609,0.008393693,0.009357565,0.00007818247,0.0003545878,0.0001486922,0.4618503],"genre_scores_gemma":[0.006987839,0.3193495,0.005661734,0.006347009,0.0026687,0.00008295692,0.0003372202,0.00005602728,0.6585091],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.03181993,"threshold_uncertainty_score":0.1064483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01516163008331269,"score_gpt":0.2673966401539736,"score_spread":0.252235010070661,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}