{"id":"W4378194556","doi":"10.1007/978-3-031-26078-0_10","title":"New Systemic Antifungal: Isavuconazole","year":2023,"lang":"en","type":"book-chapter","venue":"Emerging infectious diseases of the 21st century","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Posaconazole; Voriconazole; Itraconazole; Azole; Aspergillosis; Aspergillus fumigatus; Echinocandins; Medicine; Antifungal; Drug; Pharmacology; Biology; Immunology; Caspofungin; Dermatology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001435665,0.0006595373,0.0004203662,0.001114679,0.0003044615,0.001126772,0.0004147524,0.0009117133,0.009253304],"category_scores_gemma":[0.000172734,0.0001655748,0.0002461451,0.0007167858,0.0003644189,0.001300694,0.000498838,0.001717668,0.00506374],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005569031,"about_ca_system_score_gemma":0.0003346615,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008706672,"about_ca_topic_score_gemma":0.003405539,"domain_scores_codex":[0.9999139,0.00001184468,0.00000530486,0.00001941611,0.00003962,0.000009853794],"domain_scores_gemma":[0.9999621,0.00001370079,0.000004142131,0.000002451815,0.00001045694,0.000007068359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006347418,0.00008076578,0.00008150449,0.000649887,0.000009164709,0.0004786992,0.00009152102,0.0004031084,0.006555581,0.02167923,0.1871877,0.7827194],"study_design_scores_gemma":[0.000005184403,0.0000351256,0.0001251147,0.0001231203,0.00000613533,0.001456531,0.00001890592,0.0001632386,0.001093324,0.002569496,0.9943979,0.000005987664],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"other","genre_scores_codex":[0.00219136,0.7266099,0.006572961,0.008051425,0.007853379,0.00003826595,0.0001701633,0.0003095928,0.2482028],"genre_scores_gemma":[0.01517615,0.4576121,0.006883943,0.007019382,0.004546241,0.00005462184,0.0002977973,0.0001154601,0.5082943],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.009253304,"threshold_uncertainty_score":0.03095537,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01211429217030642,"score_gpt":0.2500974102929641,"score_spread":0.2379831181226577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}