{"id":"W4378227679","doi":"10.1039/d3sc01960h","title":"Isotope-encoded tetrahedral DNA for multiple SARS-CoV-2 variant diagnosis","year":2023,"lang":"en","type":"article","venue":"Chemical Science","topic":"SARS-CoV-2 detection and testing","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Fundamental Research Funds for the Central Universities; Sichuan University; Department of Science and Technology of Sichuan Province; National Natural Science Foundation of China","keywords":"DNA; Isotope; Tetrahedron; Computational biology; Genetics; Chemistry; Biology; Crystallography; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005072069,0.0001374442,0.0002114159,0.0001470051,0.0002140441,0.00005899704,0.000273278,0.00008164936,0.00001052328],"category_scores_gemma":[0.005571285,0.0001144077,0.0001046211,0.001661435,0.0003807274,0.000155678,0.0001182408,0.0001596862,0.0001559035],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001198711,"about_ca_system_score_gemma":0.0001360614,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005149557,"about_ca_topic_score_gemma":0.000005949819,"domain_scores_codex":[0.998288,0.000007837012,0.0002384883,0.0005126394,0.0004007514,0.0005522361],"domain_scores_gemma":[0.9989405,0.0004766771,0.000055911,0.0002753619,0.0001439987,0.0001075461],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002500726,0.00006100159,0.002865485,0.00002720624,0.000004438844,0.00002027497,0.0001050241,3.481582e-7,0.9910328,0.00006126272,0.001715539,0.004081632],"study_design_scores_gemma":[0.0008773459,0.0000752163,0.0009877383,0.00005749779,0.00001728646,0.00005511962,0.00004493224,0.01503028,0.9759757,0.0003135104,0.006417831,0.0001475538],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956697,0.0000147367,0.0006779806,0.0007752765,0.0003559403,0.0004210108,0.000008392781,0.0003938965,0.001683073],"genre_scores_gemma":[0.9942406,0.000002609945,0.003400709,0.001907151,0.0001974823,0.0001695078,0.000004684722,0.00001698311,0.00006022274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01505709,"threshold_uncertainty_score":0.6669751,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07800310710935311,"score_gpt":0.343119428860866,"score_spread":0.2651163217515129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}