{"id":"W4378470482","doi":"10.1016/j.jlr.2023.100395","title":"Cytochrome P450-soluble epoxide hydrolase derived linoleic acid oxylipins and cognitive performance in type 2 diabetes","year":2023,"lang":"en","type":"article","venue":"Journal of Lipid Research","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Rehabilitation Institute; Sunnybrook Health Science Centre; Health Sciences Centre; Sunnybrook Hospital; University of Toronto; University Health Network","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Banting and Best Diabetes Centre, University of Toronto; Natural Sciences and Engineering Research Council of Canada; Ministry of Colleges and Universities; Canada Research Chairs; University of Toronto; Canadian Institutes of Health Research; Toronto Rehabilitation Institute; Eli Lilly and Company; Alzheimer's Association","keywords":"Epoxide hydrolase 2; Stroop effect; Digit symbol substitution test; Verbal fluency test; Psychology; Linoleic acid; Trail Making Test; Verbal memory; Internal medicine; Type 2 diabetes; Cognition; Diabetes mellitus; Chemistry; Endocrinology; Biochemistry; Medicine; Neuropsychology; Psychiatry; Enzyme; Fatty acid; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001353772,0.0001069345,0.0002317335,0.000376247,0.00011306,0.00002997796,0.0001851435,0.0001449594,0.00004208332],"category_scores_gemma":[0.0003838206,0.00008873088,0.00005301173,0.0004306427,0.0001841318,0.00001506847,0.0002263531,0.0005080859,0.0000361285],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001636445,"about_ca_system_score_gemma":0.0002109188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002227666,"about_ca_topic_score_gemma":0.000006340263,"domain_scores_codex":[0.9985211,0.0002242429,0.0003083405,0.0002020078,0.0002832295,0.0004610154],"domain_scores_gemma":[0.9990388,0.00009663284,0.00009171684,0.0001102858,0.0004950626,0.0001674805],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003209902,0.00007270486,0.01232117,0.00004507761,0.00006042897,0.00007710744,0.00007678345,0.00001723547,0.981989,0.000002088588,0.003045385,0.001972012],"study_design_scores_gemma":[0.002146656,0.002386235,0.1090977,0.0001478187,0.00002119718,0.0001336186,0.0002509296,0.0006768681,0.8730322,0.00003477064,0.01190063,0.0001714131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967621,0.002053661,0.000002330335,0.0006397088,0.0001961034,0.0001242308,0.000004106789,0.000004641262,0.0002131363],"genre_scores_gemma":[0.9914095,0.007405617,0.00006483398,0.000216677,0.0004947244,0.000007652012,0.00001290429,0.00001903549,0.0003690401],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1089569,"threshold_uncertainty_score":0.361834,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05132215739516715,"score_gpt":0.3579811546381052,"score_spread":0.306658997242938,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}