{"id":"W4378470482","doi":"10.1016/j.jlr.2023.100395","title":"Cytochrome P450-soluble epoxide hydrolase derived linoleic acid oxylipins and cognitive performance in type 2 diabetes","year":2023,"lang":"en","type":"article","venue":"Journal of Lipid Research","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Rehabilitation Institute; Sunnybrook Health Science Centre; Health Sciences Centre; Sunnybrook Hospital; University of Toronto; University Health Network","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Banting and Best Diabetes Centre, University of Toronto; Natural Sciences and Engineering Research Council of Canada; Ministry of Colleges and Universities; Canada Research Chairs; University of Toronto; Canadian Institutes of Health Research; Toronto Rehabilitation Institute; Eli Lilly and Company; Alzheimer's Association","keywords":"Epoxide hydrolase 2; Stroop effect; Digit symbol substitution test; Verbal fluency test; Psychology; Linoleic acid; Trail Making Test; Verbal memory; Internal medicine; Type 2 diabetes; Cognition; Diabetes mellitus; Chemistry; Endocrinology; Biochemistry; Medicine; Neuropsychology; Psychiatry; Enzyme; Fatty acid; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007186548,0.0004117884,0.0003207038,0.0004602782,0.0002845641,0.0005658722,0.0001855639,0.0003389326,0.0009656474],"category_scores_gemma":[0.0009035316,0.0001892069,0.0005534542,0.0006165751,0.0001605845,0.0001745931,0.0002538779,0.0006382828,0.0001100313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001810062,"about_ca_system_score_gemma":0.0001799171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004807578,"about_ca_topic_score_gemma":0.004743587,"domain_scores_codex":[0.999855,0.00004970226,0.00001579199,0.00002785246,0.0000295534,0.00002214687],"domain_scores_gemma":[0.9995234,0.0001185297,0.0001901855,0.00003250056,0.00004474768,0.00009055811],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001936643,0.0004084165,0.9856835,0.00004431837,0.0004584863,0.0001709965,0.00008659218,0.0001328818,0.001185057,0.00002787772,0.0001429054,0.009722349],"study_design_scores_gemma":[0.00001456991,0.0001763681,0.9991007,0.000006806515,0.0001280873,0.00009708896,0.00003850252,0.0001950959,0.00009944852,0.00003724049,0.0001038141,0.000002245711],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970022,0.00222794,0.0001080351,0.00005969198,0.00001183273,0.000005473244,0.0001181363,0.000004260681,0.0004623885],"genre_scores_gemma":[0.9985978,0.0006856585,0.0001344996,0.0000311334,0.00002205972,0.000005877811,0.0001675075,0.000001730743,0.0003537604],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004807578,"threshold_uncertainty_score":0.009559214,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05132215739516715,"score_gpt":0.3579811546381052,"score_spread":0.306658997242938,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}