{"id":"W4378516271","doi":"10.3390/biom13050807","title":"Insulin Receptor Signaling in Health and Disease","year":2023,"lang":"en","type":"editorial","venue":"Biomolecules","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Insulin receptor; Disease; Signal transduction; Insulin; Receptor; Computational biology; Biology; Medicine; Cell biology; Internal medicine; Genetics; Insulin resistance","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003523964,0.0002982953,0.0003567799,0.000124254,0.00005841991,0.00005200828,0.0002173641,0.0004478334,0.00001454573],"category_scores_gemma":[0.001369629,0.0003019205,0.00009461839,0.0001591959,0.0001206269,0.000002422057,0.000158729,0.0002168212,0.00002782631],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003530938,"about_ca_system_score_gemma":0.001023947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001460031,"about_ca_topic_score_gemma":0.00009093524,"domain_scores_codex":[0.9980897,0.0001574039,0.0003701182,0.0006719779,0.0002936247,0.0004171714],"domain_scores_gemma":[0.998935,0.00005882305,0.0001700503,0.0003366474,0.00007378156,0.0004256643],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001213412,0.00003464222,0.00003075577,0.0003523414,0.00003678913,0.000006787911,0.00003821736,0.000002533936,0.00497973,0.0000198486,0.973465,0.02091202],"study_design_scores_gemma":[0.0005460958,0.0001078248,0.00001125149,0.0002189887,0.0000118038,8.236646e-8,0.00004224527,0.000004430919,0.002100566,0.00008559077,0.9965482,0.0003229702],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"editorial","genre_scores_codex":[0.006524831,0.5755957,0.00003516528,0.0001136793,0.4166953,0.000236585,0.0007455843,0.00003205443,0.00002109816],"genre_scores_gemma":[0.0007528455,0.4334669,0.000268854,0.000454252,0.5589814,0.0001283081,0.005171469,0.0001499039,0.0006260801],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.142286,"threshold_uncertainty_score":0.9999433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009619256098848453,"score_gpt":0.2764874701327105,"score_spread":0.2668682140338621,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}