{"id":"W4378516273","doi":"10.1002/pbc.30436","title":"Feasibility of combining temsirolimus to vincristine, dactinomycin, cyclophosphamide, and vincristine and irinotecan chemotherapy for children with intermediate‐risk rhabdomyosarcoma: A report from Children's Oncology Group","year":2023,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Manitoba; CancerCare Manitoba","funders":"National Cancer Institute; Pfizer","keywords":"Temsirolimus; Medicine; Mucositis; Vincristine; Internal medicine; Rhabdomyosarcoma; Regimen; Febrile neutropenia; Oncology; Irinotecan; Surgery; Neutropenia; Chemotherapy; Cyclophosphamide; Cancer; Sarcoma; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001068611,0.0003891058,0.0004665753,0.0001404099,0.0002312201,0.0002883674,0.000351982,0.0002696645,0.0007622035],"category_scores_gemma":[0.0008579444,0.0001796136,0.0006692012,0.0001568612,0.0003518343,0.0002852434,0.0001992371,0.0007692985,0.0001851742],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008058839,"about_ca_system_score_gemma":0.0007195135,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009405558,"about_ca_topic_score_gemma":0.002312345,"domain_scores_codex":[0.9996029,0.0001704341,0.0000428794,0.00005859505,0.00007555174,0.00004965751],"domain_scores_gemma":[0.9995133,0.0001794033,0.0001249133,0.00005027411,0.00003811537,0.00009401527],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.05551222,0.00891186,0.2394003,0.001436999,0.001942636,0.002413111,0.001089276,0.005503431,0.2766382,0.0004741214,0.002255907,0.404422],"study_design_scores_gemma":[0.01558899,0.4950624,0.3009737,0.0001913333,0.001833193,0.009764813,0.000392261,0.002722608,0.1563895,0.000166469,0.0168524,0.00006231101],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974375,0.001364608,0.0004002919,0.0000856085,0.000006404132,0.000144054,0.00006690776,0.00001574603,0.0004789708],"genre_scores_gemma":[0.9962354,0.000999723,0.002124968,0.00007446912,0.0000185557,0.00009738184,0.0002482115,0.00001060372,0.0001907339],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001068611,"threshold_uncertainty_score":0.005847156,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01459416061291698,"score_gpt":0.2970730833337152,"score_spread":0.2824789227207982,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}